OBJECTIVE Our objective is to estimate and compare the prevalence of selected adverse consequences associated with unmet need for assistance among a socioeconomically and medically vulnerable subgroup of the older adult population, those who are dually eligible for Medicare and Medicaid, with those eligible for Medicare only. METHOD Using data from the National Health and Aging Trends Study (...

By Gelfand-Neumark duality, the category C∗Alg of commutative C∗algebras is dually equivalent to the category of compact Hausdorff spaces, which by Stone duality, is also dually equivalent to the category uba` of uniformly complete bounded Archimedean `-algebras. Consequently, C∗Alg is equivalent to uba`, and this equivalence can be described through complexification. In this article we study u...

Laboratory diagnosis of human ehrlichioses is routinely made by an indirect immunofluorescence assay (IFA) using cultured ehrlichia-infected whole cells as antigen. Concern has been raised that incorrect diagnoses of human monocytic ehrlichiosis (HME) or human granulocytic ehrlichiosis (HGE) may be made on the basis of serologic cross-reactivity between Ehrlichia chaffeensis and the agent of HG...

Divergences, also known as contrast functions, are distance-like quantities defined on manifolds of non-negative or probability measures and they arise in various theoretical and applied problems. Using ideas in optimal transport, we introduce and study a parameterized family of $L^{(\pm \alpha)}$-divergences which includes the Bregman divergence corresponding to the Euclidean quadratic cost, a...

Measures of divergence between two points play a key role in many engineering problems. One such measure is a distance function, but there are many important measures which do not satisfy the properties of the distance. The Bregman divergence, KullbackLeibler divergence and f -divergence are such measures. In the present article, we study the differential-geometrical structure of a manifold ind...

Substantial rates of substance use comorbidity have been observed among veterans with Post-Traumatic Stress Disorder (PTSD), highlighting the need to identify patient and program characteristics associated with improved outcomes for substance abuse. Data were drawn from 12,270 dually diagnosed veterans who sought treatment from specialized intensive Veterans Health Administration PTSD programs ...

The first quadruple luminescent sensor is presented which enables simultaneous detection of three chemical parameters and temperature. A multi-layer material is realized and combines two spectrally independent dually sensing systems. The first layer employs ethylcellulose containing the carbon dioxide sensing chemistry (fluorescent pH indicator 8-hydroxy-pyrene-1,3,6-trisulfonate (HPTS) and a l...

Dually targeted mitochondrial proteins usually possess an unconventional mitochondrial targeting sequence (MTS), which makes them difficult to predict by current bioinformatics approaches. Human apurinic/apyrimidinic endonuclease (APE1) plays a central role in the cellular response to oxidative stress. It is a dually targeted protein preferentially residing in the nucleus with conditional distr...

Both the MAP kinase and PI3K/Akt pathways play an important role in the pathogenesis of melanoma. We conducted the present study to test the hypothesis that targeting the two pathways to potently induce cell inhibition accompanied with thyroid iodide-handling gene expression for adjunct radioiodine ablation could be a novel effective therapeutic strategy for melanoma. We used specific shRNA app...