نتایج جستجو برای: regulation of cell metabolism
تعداد نتایج: 21404276 فیلتر نتایج به سال:
objective: silybin is a polyphenol with anti-oxidant and anti-cancer properties. the poor bioavailability of some polyphenols can be improved by binding to phosphatidylcholine. in recent years, studies have been conducted to evaluate the anti-cancer effect of silybin. we studied the effect of silybin and silybin-phosphatidylcholine on esr1 and esr2 gene expression and viability in the t47d brea...
Abstract Although NAD +levels modulate metabolism, how this regulates immunometabolism/inflammation remains unclear. Employing Nicotinamide Riboside (NR) to boost NAD, we explored T H17-linked inflammatory in Psoriasis. Primary Psoriasis CD4 +T cells exposed NR reduced IL-17 secretion and RNA-seq/pathway analysis implicated modulating sequestosome 1 (SQSTM1/p62)-coupled oxidative stress. In par...
The growth hormone in fish is involved in most of the physiological processes in the body, including the growth of soft and hard tissues, protein metabolism, lipid and carbohydrate, ionic regulation and osmotic balance, reproductive function, and immune system. Since the study on the use of growth hormone in ornamental fish is not available, the present study aims to regulate neuroendocrine gro...
Cellular metabolism is a key regulator of cell fate, including fate in pluripotent stem cells. Now in Cell Stem Cell, Zhang et al. (2016) show that Lin28 controls the metabolic transition from naive to primed pluripotency by directly repressing oxidative metabolism genes and metabolic intermediates involved in epigenetic regulation independently of let-7.
Metabolism generates energy for organisms to sustain all kinds of biological functions, such as cell growth and cell apoptosis. The immune system requires an adequate energy supply for its optimal function [1]. During the activation and differentiation of T cells, the balance between glycolysis and lipid oxidation shifts in order to cater for the cell’s energy requirements [2]. There is increas...
MicroRNAs (miRNAs) involved in regulation of the genes. The CCAAT/enhancer-binding protein-α (CEBPα) is a crucial transcription factor for normal hematopoiesis and cell cycle that frequently disrupted in human acute myeloid leukemia (AML). The miR-182 up-regulation in several malignant diseases such as AML was reported, in the other hand bioinformatics analysis revealed CEBPα targeted by miR-18...
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