BACKGROUND Hodgkin lymphoma is uncommon in the U.S. general population; however, Hodgkin lymphoma risk is elevated in people with human immunodeficiency virus (HIV) infection. Thus, despite the low HIV prevalence in the United States, the HIV epidemic may have contributed substantially to the general population burden of Hodgkin lymphoma. METHODS We used data from 14 U.S. cancer registries in...

Radioimmunotherapy of indolent non-Hodgkin lymphoma (NHL) has achieved objective response rates in clinical trials comparable with standard rituximab with cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy, but is relatively underused in routine practice. In this article, we report our clinical experience in 142 consecutive patients who received iodine-131 rituximab radioim...

Is peripheral stem cell mobilization followed by autologous stem cell transplantation (ASCT) feasible in patients with human immunodeficiency virus (HIV)- associated lymphoma (HIV-L)? Studies have demonstrated that, in the HIV- negative (HIV(-)) setting, ASCT may improve lymphoma-free survival in high-risk non-Hodgkin lymphoma (NHL) or relapsed Hodgkin disease (HD) and NHL. Given the poor progn...

Immune checkpoint inhibition (ICI) has demonstrated an overall excellent benefit-to-risk profile in the treatment of classical Hodgkin lymphoma (cHL); however, cure remains exception to rule. The German Study Group (GHSG) identified several areas unmet need for ICI development cHL. First, we aim better understand role immune checkpoints interplay between Hodgkin/Reed-Sternberg malignant cells a...

Intravascular large B-cell lymphoma (IVLBCL) is a rare, aggressive and often fatal non-Hodgkin lymphoma characterized by preferential growth of malignant B-cells within the lumina of small vessels. Rituximab plus anthracycline-based chemotherapy is the current standard regimen for IVLBCL, however it has minimal efficacy in relapsed or refractory diseases. Recent clinical trials have shown a sig...

neurolymphomatosis is a rare manifestation of non-hodgkin lymphoma characterized by infiltration of peripheral nerves, nerve roots, plexus and cranial nerves by malignant lymphocytes. this report presents positron emission tomography/computed tomography (pet/ct)imaging with 2-deoxy-2-18f-fluoro-d-glucose (18f-fdg) in 3 cases of non-hodgkin lymphoma with nerve infiltration, including one newly d...