نتایج جستجو برای: related mucosal damage prophylaxis
تعداد نتایج: 1424708 فیلتر نتایج به سال:
Distal deep vein thrombosis (DVT) can range from being asymptomatic, to resulting in long term valvular damage resulting in chronic venous insufficiency. Proximal propagation can result in more serious pulmonary embolism. The overall incidence of DVT, including both radiologically diagnosed asymptomatic DVT and symptomatic DVT, post THA in early studies was reported to be as high as 70% without...
Disruption of the intestinal epithelial barrier allows bacterial translocation and predisposes to destructive inflammation. To ensure proper barrier composition, crypt-residing stem cells continuously proliferate and replenish all intestinal epithelial cells within days. As a consequence of this high mitotic activity, mucosal surfaces are frequently targeted by anticancer therapies, leading to ...
Crohn's disease aetiology is multifactorial and remains enigmatic. However, animal models show that disease heterogeneity is probable, in that more than one defective mucosal mechanism can produce the same clinical phenotype. For example, Crohn's-like lesions are reported after compromise of mucosal integrity per se in the presence of an intact immune system, through altered expression of mucos...
Recent studies indicate an expression of mitogen-inducible cyclooxygenase (COX-2) in gastric mucosa. Rebamipide, a mucoprotective agent enhances prostaglandin (PG) synthesis. The present study was designed to clarify the mechanism for rebamipide-induced mucosal protection. Male Sprague-Dawley rats were administered 5, 15, or 50 mg/kg/day rebamipide for 14 days. The expression of constitutive cy...
Proton pump inhibitors (PPIs) are antiulcer agents that have both gastric antisecretory and mucosal protective actions. The mechanisms of PPI-induced gastric mucosal protection are not known. The present study was designed to examine the mechanism for lansoprazole-induced gastric mucosal protection in rats. Rats were given 0.5, 5, and 50 mg/kg/day lansoprazole alone or both lansoprazole (50 mg/...
Mucosal damage is a key feature of inflammatory bowel diseases (IBD) and healing the mucosa an endpoint IBD treatment that often difficult to achieve. Autonomic neurons parasympathetic sympathetic nervous system may influence intestinal epithelial cell growth modulating innervation could for reason serve as interesting therapeutic option improve mucosal healing. Understanding biological process...
BACKGROUND AND AIMS Persistent intestinal damage is associated with higher complication rates in celiac disease. We aimed to assess the potential modifiers of mucosal recovery. MATERIALS AND METHODS We screened databases (PubMed, Embase, Cochrane Trials, and Web of Science) for papers on celiac disease. Papers discussing (1) celiac patients (2) follow-up biopsy and (3) mucosal recovery after ...
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