background: germline mutations in mmr genes are reported to be present in more than 70% of hnpcc cases. but, there is a paucity of data regarding the importance of defect of mmr system in the gastric cancer in general. so, in this study, we used ihc stain formlh1,msh2, pms2 andmsh6 to reveal profile ofmmr expression in patients with gastric cancer. materials and methods: this study was performe...

background: colorectal cancer is the third cause of cancer death in western countries. age, inadequate diet, obesity, inactivity and genetic changes are some of the risk factors of colorectal cancer. correlation of genetic diversity in homologous recombination repair system with cancer was evaluated in many recent studies. this study was done to investigate the correlation of t241m polymorphism...

objective(s):although previous studies have confirmed the beneficial effects of human umbilical cord matrix stem cell (hucm) transplantation post myocardial infarction (mi), but this stem cell resource has no potential to induce angiogenesis. in order to achieve the process of angiogenesis and cardiomyocyte regeneration, two required factors for cardiac repair agents were examined namely; hucm ...

this study has examined the relationship between the xpd lys 751 gln polymorphism and colorectal cancer in 88 patients and their 88 age and sex-matched controls. genomic dna from peripheral whole blood was extracted using standard method to determine the genotype of subjects with rflp-pcr analysis. although this study shows cancer patients harbor more heterozygous genotype (xpd lys 751 gln) (or...

abstract hypoplastic right ventricular is a rare congenital heart disease. a few cases have been reported. we presented a case with hypoplastic right ventricular and multiple associated anomaly (ventricular septal defect, atrial septal defect and pulmonary stenosis) in whom the main concern was whether biventricular repair or fontan type surgery would be the optimal management in this patient. ...

In this case report, we described a 74-year-old female patient with major complaint of respiratory problemsdyspnea after meal. Chest X-ray of the patient revealed a  gianttype IV hiatal hernia. Preoperative evaluations of the patient included esophagoscopy, esophageal manometry, barium swallow, and CT-scan. Repair of the hernia was performed using a dual mesh on the diaphragm and partial anteri...

background: pain is one of the side effects of episiotomy. the virtual reality (vr) is a non-pharmacological method for pain relief. the purpose of this study was to determine the effect of using video glasses on pain reduction in primiparity women during episiotomy repair. methods: this clinical trial was conducted on 30 primiparous parturient women having labor at omolbanin hospital (mashhad,...

conclusions the results of this study showed that the meticulous microsurgical nerve repair, which was performed using the vein tubulization induced significantly better sciatic nerve regeneration. however, the addition of bone marrow mesenchymal stem cell to vein conduit failed to promote any significant changes in regeneration outcome. results all animals tolerated the surgical procedures and...

objectives: the aim of this retrospective observational study was to identify local and clinical factors related to the need of surgical repair. patients and methods: in this retrospective study, 122 (0.06%) fpas treated among 21060 patients over a period of five years were assessed. patient characteristics and therapeutic procedures were analyzed through hospital records. results: there were 1...