farzaneh vafaee neurogenic inflammation research center, department of physiology, school of medicine, mashhad, university of medical sciences, mashhad, iran mahmoud hosseini neurocognitive research center, department of physiology, school of medicine, mashhad, university of medical sciences, mashhad, iran zahra hassanzadeh department of biology, faculty of basic sciences, fars science and research branch, islamic azad university, shiraz, iran mohammad amin edalatmanesh department of biology, faculty of basic sciences, fars science and research branch, islamic azad university, shiraz, iran hamid reza sadeghnia pharmacological research center of medicinal plants, school of medicine, mashhad university of medical sciences, mashhad, iran masoumeh seghatoleslam department of anatomy and cell biology, school of medicine, mashhad university of medical sciences, mashhad, iran