نتایج جستجو برای: reporter gene assay
تعداد نتایج: 1313861 فیلتر نتایج به سال:
Recently, long noncoding RNAs (lncRNAs) have been reported to play important role in the pathogenesis of various cancers. However, functions RNF185-AS1 hepatocellular carcinoma (HCC) remain unknown. The expression HCC cells and tissues was measured by quantitative real-time polymerase chain reaction (qRT-PCR). effects on tumor cell proliferation, migration invasion were assessed Cell Counting K...
We have designed and synthesized estrogen antagonists bearing dicarba-closo-dodecaborane (carborane) as a hydrophobic pharmacophore based on the structure of 1-(4-hydroxyphenyl)-1,12-dicarba-closo-dodecaborane, a potent estrogen agonist that we reported previously. Compounds with a long alkyl chain bearing an amide moiety on the carborane skeleton (6, 7) showed estrogen antagonistic activity in...
Validation of a cell-based colorimetric reporter gene assay for the evaluation of Type I Interferons
The traditional antiviral assays for the determination of interferon potency are reported to have considerable variability between and within assays. Although several reporter gene assays based on interferon-inducible promoter activities have been reported, data from comprehensive validation studies are lacking and few studies have been conducted to analyze the variant forms of interferons, whi...
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