This study evaluated immunomodulatory properties and the sub-acute toxicity profile of two fractions of the aqueous alcoholic extract of the dried calyx of Hibiscus sabdariffa in experimental animals. Immunomodulatory activity was evaluated using red blood cell-induced immunostimulation. The fractions were not found to be toxic after 7-day administration, though there was severe weight loss wit...

We investigated the repellency and toxicity of eight plant extracts containing celangulin, cnidium lactone, matrine, nicotine, pyrethrins, rotenone, stemonine veratrine against western flower thrips (Frankliniella occidentalis Pergande; Thysanoptera: Thripidae). Flowers treated with 0.05% rotenone harbored fewer in two- multiple-choice bioassays. When evaluated at concentrations varying from 0....

Thirty-six fluoroaliphatic sulfones were tested to determine their residual toxicity to Solenopsis invicta Buren in soil. Six of the compounds gave >90% kill of the ants after they were exposed for 4 days at 10 ppm. When tested at 1.0 ppm, only one compound, AI3-10841, gave appreciable mortality. This compound was tested at 10 ppm in soil held outdoors under ambient summer conditions. Mortality...

The water-soluble fractions of three crude and two refined oils reduced the growth rate and maximum cell density of the marine bacterium Serratia marinorubra grown in batch culture. The weathering of a crude and a refined oil was simulated in the laboratory. The water-soluble fractions remaining from this process were more toxic to S. marinorubra than were the parent unweathered oils. Increases...

Anticoagulant rodenticides act at the hepatic level where they are more or less fixed according to their lipophilic nature. The studies on kinetics and metabolism carried out with no toxic doses are useful to know how products act but do not allow to anticipate the toxicity risks for non target species, because of low residual contents. These risks can only be assessed after the administration ...

The contact toxicity activity of an essential oil extracted from Acorus calamus (L.) (Acoraceae) was evaluated against the phytophagous spider mites Tetranychus urticae Koch and macfarlanei Baker & Pritchard (Acari: Tetranychidae) predatory mite Amblyseius longispinosus (Evans) Phytoseiidae). Adult mortality 24 h following application 5% (v/v) concentration exceeded 90% for T. macfarlanei. Appl...

Oxidative coupling reaction of phenol mediated by birnessite was studied in aqueous phase and soil. Phenol was readily transformed by birnessite and almost all phenol disappeared in both samples after 24 hours of reaction. Phenol transformation kinetics was investigated by plotting reaction time against logarithm concentrations of residual phenol, revealing that exponential decrease of phenol w...

rapid half-life of DXL (about 4min) causing no accumulation of the drug in the central compartment after repeated administration. So these differences in DXL plasma concentrations looked accidental. The observed transient increase of DXL plasma concentrations during HD is probably due to altered protein binding of the drug. To evaluate DXL toxicity, blood-count controls were taken in periodic i...

PURPOSE To report a case of primary acquired melanosis (PAM) successfully treated with combined topical mitomycin C and interferon-α2b. CASE REPORT A 75-year-old man presented with an extensive unilateral pigmented lesion involving 360° of the bulbar conjunctiva, extending to the fornices and palpebral conjunctiva. Map biopsy confirmed PAM with local atypia. Treatment was initiated with mitom...

Adverse reactions develop in roughly one third of patients treated with gold, the proportion varying from 5",, to 80O, in several reported series.' Eosinophilia occurs in roughly 5O, of patients and has been directly correlated with the development of gold toxicity.2 Vasomotor reactions to gold are not uncommon, but whether they indicate the development of more serious gold toxicity is unknown....