The load resistance factor according to the target reliability level was proposed using 16 vertical breakwaters constructed along coast of Korea. Limit state functions for sliding and overturning limit states were defined. Reliability analysis performed obtain sensitivity function design variables. partial safety factors variable obtained sensitivity, calculated in turn. representative value by...

Antibiotic selection pressure and genetic associations may lead to the cooccurrence of resistance and virulence in individual pathogens. However, there is a lack of rigorous epidemiological evidence that demonstrates the cooccurrence of resistance and virulence at the population level. Using samples from a population-based case-control study in 25 villages in rural Ecuador, we characterized res...

1. E8cherichia coli with an R-factor conferring resistance to tetracycline was induced to high-degree resistance by pre-exposure to the antibiotic. The degree of resistance was drastically lowered by subjecting the cells to osmotic shock. 2. Resistance to tetracycline was rapidly restored by incubating the shocked cells in a glucose-salts medium containing shock proteins prepared from tetracycl...

background: helicobacter pylori (h. pylori) resistance to antibiotics has become a global problem and is an important factor in determining the outcome of treatment of infected patients. the purpose of this study was to determine the h. pylori resistance to clarithromycin, metronidazole, and amoxicillin in gastrointestinal disorders patients. materials and methods: in this study, a total of 260...

A new factor V mutation associated with resistance to activated protein C and thrombosis (factor V Cambridge, Arg306-->Thr) was found in one patient from a carefully selected group of 17 patients with venous thrombosis and confirmed APC resistance in the absence of the common Gln506 mutation. The Arg306 mutation was also present in a first degree relative who also had APC resistance. Other pote...

A common mutation in the factor V gene, the Leiden mutation, is the most frequent genetic cause of resistance to activated protein C (APC). Recent studies have shown that the prevalence of APC resistance is associated with severe pregnancy-induced hypertension (PIH). Our objective was to determine whether the factor V Leiden mutation is more prevalent in patients who developed severe PIH than i...