Certain similarities between preeclampsia and insulin resistance syndrome suggest a possible link between the 2 diseases. The aim of our study was to evaluate 3 insulin sensitivity (IS) indexes (fasting homeostasis model assessment IS [ISHOMA], quantitative insulin sensitivity check index [ISQUICKI], and oral glucose IS [OGIS]) early and late in pregnancy in a large number of normotensive pregn...

2 3 The prevalence of antibiotic-resistant bacteria in the marine environment is a growing 4 concern, but the degree to which marine mammals, seabirds and fish harbor these organisms is 5 not well documented. This project sought to identify the occurrence and patterns of antibiotic 6 resistance in bacteria isolated from vertebrates of coastal waters in the northeastern United 7 States. 472 isol...

BACKGROUND Although non-alcoholic fatty liver disease is the hepatic manifestation of metabolic syndrome, its influence on hypertension development is poorly understood. We investigated whether fatty liver disease, as assessed by the fatty liver index, could predict the development of hypertension independently of systemic insulin resistance, inflammatory status and adipokine levels. METHODS ...

BACKGROUND AND OBJECTIVES A 1-year multicenter prospective randomized controlled study was conducted on the effects of vitamin E-bonded polysulfone dialyzers on erythropoiesis-stimulating agent response in hemodialysis patients. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Major inclusion criteria were use of high-flux polysulfone dialyzers with 50-70 ml/min β2-microglobulin clearance over 3...

OBJECTIVE Central (truncal) adiposity is associated strongly with insulin resistance and diabetes. There are very few reports comparing methods of trunk fat measurement in their ability to predict glycaemia and insulin resistance. We report a comparative analysis of different trunk fat measurements in predicting glycaemia and insulin resistance in middle aged Indian men. MATERIALS AND METHODS...

CONTEXT Methods to directly measure insulin resistance are invasive, complex, and costly. Surrogate indexes derived from the oral glucose tolerance test (OGTT) have been developed, but few studies have systematically analyzed these indexes. OBJECTIVE We examined the relation of surrogate and direct measures of insulin resistance to metabolic variables. DESIGN AND SETTING We conducted a cros...

surgery and to enhance our understanding of the pathophysiology of mitral stenosis. Although surgery produced a significant increase in calculated mitral valve area, the degree of improvement varied markedly. The younger patients had the greater increase in mitral valve area. The change in cardiac index and pulmonary vascular resistance correlated well with the change in mitral valve area. Only...

Insulin resistance is a pathophysiologic link to development of several metabolic disorders in obese subjects. The aim of this study is to evaluate the association between obesity and insulin resistance using HOMA-IR index in normoglycemic obese subjects and to compare the results with the result of healthy non obese subjects. The importance is to identify the subjects in risk for developing pr...

Leukotriene D4, a constituent of slow-reacting substance of anaphylaxis, elicits a pressor response followed by hypotensive shock in spontaneously hypertensive rats but not in other rats. Hemodynamic mechanisms underlying this pattern in spontaneously hypertensive rats, pithed and vagotomized to eliminate circulatory reflexes, were studied using radiolabeled microspheres. One minute after leuko...