the recently emerged middle east respiratory syndrome coronavirus (mers-cov) emerged in the middle east region in 2012. the virus is phylogenetically related to bat cov, but other animal species like camels and goats may potentially act as an intermediate host by spreading the virus to humans. this virus is thought to cause a severe disease in patients with underlying comorbidities. laboratory ...

respiratory syncytial virus (rsv) is the major cause of lower respiratory tract infections in infants,and also an important factor for hospitalization during the winter months. to determine the prevalence and importance of rsv as a cause of acute lower respiratory tract infection, we carried out a prospective study during 5 months period from november to march 1998 in 6 pediatric hospitals. a n...

Abstract Netherton syndrome is a rare genetic disorder inherited in an autosomal recessive pattern. Mutations the serine protease inhibitor Kazal-type 5 ( SPINK5 ) gene are responsible for this disorder. can have multisystemic effects primarily involving hair, skin and immune system. Currently, no definitive treatment has been reported beyond supportive care. Herein, we report case of newborn d...

leigh syndrome is a severe progressive neurodegenerative disorder with different clinical presentationsthat usually becomes apparent in the first year of life and rarely in late childhood and elderly years. it is causedby failure of mitochondrial respiratory chain and often results in regression of both mental and motor skills and might even lead to death. in some of the inherited neurodegenera...

OBJECTIVE Many evidences raise the possibility that the panic disorder (PD) patients with respiratory subtype (RS) may have characteristic structural abnormalities. We aimed to explore the structural differences between PD patients with and without the respiratory symptoms. METHODS Patients with PD were recruited from the Department of Psychiatry at Korea University Anam Hospital. Respiratory...

OBJECTIVES There is evidence of baseline respiratory abnormalities in panic disorder (PD), but whether they are specific to PD remains unclear. To investigate this issue, we meta-analyzed results from studies comparing baseline respiratory and hematic variables between subjects with PD and subjects with other anxiety disorders. METHODS A literature search in bibliographic databases was perfor...

chronic granulomatous disease (cgd) is a rare primary immunodeficiency disease. although the most affected patients are diagnosed in childhood, there are several reports of the disease presenting in adult patients. here we present a 40 years old man who was admitted in hospital due to respiratory symptoms and ground glass pattern in high resolution computed tomography of lung. open lung biopsy ...

pompe disease, also termed glycogen storage disease type ii or acid maltase deficiency, caused by deficient activity of acid alpha-glucosidase (gaa), the glycogen degrading lysosomal enzyme. as a result, massive lysosomal glycogen deposits in the numerous organs including the muscles. in pompe disease weakness of truncal muscles is a prominent presentation which results in respiratory failure a...