Mesoporous silica nanoparticles grafted with light-responsive polymer on the outer surface were developed as novel nanogated ensembles, which allow encapsulation and release of drug and biological molecules under light irradiation.

The plasma polymerization of NIPAAM and titanium isopropoxide monomers into responsive ultrathin films with responsive optical properties using plasma enhanced chemical vapor deposition is reported. The composite ultrathin films possess a large window for potential changes in their refractive index from 1.60 to 1.95. We demonstrated that these polymer films exhibit fast (transition time below 2...

Acetalated dextran (Ac-DEX) is a pH-responsive derivative polymer. Ac-DEX and its functional derivatives have been formulated as nano- or microparticles for drug delivery applications in the biomedical field.

Mesoporous silica nanoparticles (MSNPs) have garnered a great deal of attention as potential carriers for therapeutic payloads. However, achieving triggered drug release from MSNPs in vivo has been challenging. Here, we describe the synthesis of stimulus-responsive polymer-coated MSNPs and the loading of therapeutics into both the core and shell domains. We characterize MSNP drug-eluting proper...

Introduction The development of effective culture methods is very important in regenerative medicine. This is because they may be able to contribute to the advancement of medicine. Since the liver plays an important and complex metabolic role, the development of a practicable culture method to maintain long-term hepatocyte function is highly desirable. However, hepatocytes lose their liver-spec...

Responsive polymer-based materials (or smart materials) have found numerous uses over the years due to their ease of synthesis and various responsivities/functionalities. Of them, stimuli-responsive hydrogel particles (microgels) have generated a lot of interest, and have been used for a number of applications, most importantly for this submission is their use as components of photonic material...