Open MPI provides an implementation of the MPI standard supporting native communication over a range of high-performance network interfaces. Los Alamos National Laboratory (LANL) and Oak Ridge National Laboratory (ORNL) collaborated on creating a port for Cray XE and XK systems. That work has continued and with the release of version 1.8 Open MPI now conforms to MPI-2.2 and MPI-3.0 on Cray XE, ...

The MPI datatype functionality provides a powerful tool for describing structured memory and file regions in parallel applications, enabling noncontiguous data to be operated on by MPI communication and I/O routines. However, no facilities are provided by the MPI standard to allow users to efficiently manipulate MPI datatypes in their own codes. We present MPITypes, an open source, portable lib...

A large number of MPI implementations are currently available, each of which emphasize different aspects of high-performance computing or are intended to solve a specific research problem. The result is a myriad of incompatible MPI implementations, all of which require separate installation, and the combination of which present significant logistical challenges for end users. Building upon prio...

BACKGROUND Older adults are often excluded from clinical trials. Decision making for administration of statins to older patients with diabetes mellitus (DM) is under debate, particularly in frail older patients with comorbidity and high mortality risk. We tested the hypothesis that statin treatment in older patients with DM was differentially effective across strata of mortality risk assessed b...

In this paper we examine the topic of writing fault-tolerant Message Passing Interface (MPI) applications. We discuss the meaning of fault tolerance in general and what the MPI Standard has to say about it. We survey several approaches to this problem, namely checkpointing, restructuring a class of standard MPI programs, modifying MPI semantics, and extending the MPI specification. We conclude ...

This paper examines the topic of writing fault-tolerant MPI applications. We discuss the meaning of fault tolerance in general and what the MPI Standard has to say about it. We survey several approaches to this problem, namely checkpointing, restructuring a class of standard MPI programs, modifying MPI semantics, and extending the MPI specification. We conclude that within certain constraints, ...

Chiral 2-methylpiperidine (2-MPI) is an important building block that has potential for applications in pharmaceuticals and pesticides. In this study, we observed the hydrolase Arthrobacter sp. K5 exhibits high (S)-selectivity toward rac-N-pivaloyl-2-MPI to yield (S)-2-MPI with 80.2% enantiomeric excess (ee) a 38.2% conversion. The hydrolase, which was identified by analyses of partial amino ac...

UNLABELLED Transient ischemic dilation (TID) in the setting of abnormal stress-rest cardiac SPECT myocardial perfusion imaging (MPI) has been linked with increased cardiovascular risk. However, the significance of TID in the setting of an otherwise normal SPECT MPI study has not been clearly established. In this study, cardiac CT was used to evaluate the prevalence of atherosclerotic lesions an...