Retinopathy of prematurity (ROP) causes 100,000 new cases of childhood blindness each year. ROP is initiated by oxygen supplementation necessary to prevent neonatal death. We used organ systems pharmacology to define the transcriptomes of mice that were cured of oxygen-induced retinopathy (OIR, ROP model) by hypoxia-inducible factor (HIF) stabilization via HIF prolyl hydroxylase inhibition usin...

Background: Retinopathy of prematurity (ROP) is an important cause preventable blindness in children. It a serious and underestimated complication treatment among preterm low-birth weight babies unless recognized treated early. Objective: The objective this study was to estimate the prevalence ROP infants Neonatal Intensive Care Unit (NICU) tertiary hospital increase awareness early screening p...

purpose : to evaluate the efficacy of autologous plasmin in pediatric vitrectomy and to report the anatomic outcomes of autologous plasmin assisted pediatric vitrectomy methods : in an interventional prospective study, thirty-four pediatric patients with vitreoretinal disorders who needed vitrectomy during 2008 to 2010, included in the study. the patients were divided into two groups: the retin...

PURPOSE Macular anatomic abnormalities were examined by optical coherence tomography (OCT) imaging in premature children and compared with those of full-term children. METHODS In a prospective case-control study, premature patients 7 to 14 years of age were divided into three groups (group I, laser-treated retinopathy of prematurity [ROP]; group II, spontaneously regressed ROP; group III, no ...

Although retinopathy of prematurity (ROP) is clinically characterized by abnormal retinal vessels at the posterior pole of the eye, it is also commonly characterized by vascular abnormalities in the anterior segment, visual dysfunction which is based in retinal dysfunction, and, most commonly of all, arrested eye growth and high refractive error, particularly (and paradoxically) myopia. The oxy...

Introduction: Since retinopathy of prematurity (ROP) is a preventable cause blindness in children, evaluation declared criteria for their screening crucial. The aim this study to evaluate the incidence disease Nikukari Eye Hospital according gestational age and neonatal birth weight. Methods: In cross-sectional study, after determining frequency based on patients referred ROP clinic, neonates w...

The question as to whether people totally blind since infancy process allocentric or external spatial information like the sighted has caused considerable debate within the literature. Due to the extreme rarity of the population, researchers have often included individuals with retinopathy of prematurity (RoP--over oxygenation at birth) within the sample. However, RoP is inextricably confounded...

OBJECTIVE To determine the risk factors and outcomes of retinopathy of prematurity (ROP) in infants with a birth weight of 1,501-2,000 g. MATERIALS AND METHODS Clinical characteristics and risk factors were compared and nonconditional logistic regression analysis was performed to determine independent predictors for ROP. RESULTS There were 54 (9.8%) cases of ROP in 553 patients with a birth...

AIM (1) To determine if expression of the blood-tissue barrier associated glucose transporter GLUT1 is preserved by the neovasculature of retinopathy of prematurity (ROP), in contrast with the reported loss of GLUT1 expression in preretinal vessels of proliferative diabetic retinopathy. (2) To compare the vascular immunophenotype of ROP to juvenile haemangioma, another perinatal neovascular dis...

purpose: to determine the incidence, severity and risk factors for retinopathy of prematurity (rop) in premature infants with late retinal examination at farabi hospital from 2001 to 2006. methods: in a cross-sectional study, hospital records of premature infants who were examined later than 9 weeks after birth were reviewed for possible risk factors of rop including gender, singleton or multip...