In the preceding article (1) evidence was presented which would not support the conception of a specific etiological relationship between respiratory infections and rheumatic fever in children. The designation, " streptococcal " respiratory infection, based solely on bacteriological findings, was questioned. During these observations as to the relation between respiratory infections and rheumat...

In recent publications, Rinehart and Mettier (1933, 1934), and Rinehart, Connor and Mettier (1934) have offered evidence to the effect that chronic scurvy with superimposed infection in guinea pigs results in a histopathological picture "strikingly similar" to that found in rheumatic fever in human beings. Moreover, they have cited other experimental, epidemiological, and clinical data in favor...

1. During the Spring of 1928, 29 patients with acute rheumatic fever were subjected to blood cultures, of whom 9, or 31 per cent, yielded a streptococcus. During the Spring of 1929, 31 patients with acute rheumatic fever were studied by blood cultures, of whom 26, or 83.9 per cent, yielded a streptococcus. The higher percentage of positive cultures in the 1929 series appears to have been due to...

Although recurrent rheumatic fever in adults is uncommon and the recurrence rate declines with age and with the interval from the attack, we describe a patient who has had four attacks of rheumatic fever, two in childhood and two in adult life.

Despite dramatic gains of the last century, acute rheumatic fever and rheumatic heart disease remain major preventable causes of morbidity and mortality in many parts of the world.

would be of use to know by pulsed Doppler echocardiography whether or not the origin of the murmur in question is consistent with a rheumatic process. When there has been no firm basis for the diagnosis of rheumatic fever, and pulsed Doppler echocardiography shows only a VSD, removal of the diagnosis of rheumatic fever and discontinuation of rheumatic fever prophylaxis may be considered. In cas...

rhe INFECTIVE group consists of 674. cases, or 53.8 per cent. of the total admissions, and of this group the rheumatic had 4153 cases, one-third of the total, or 67.2 per cent. of the Infective group. In this group are placed those cases with a definite history of rheumatic fever, chorea, growing pains, tonsillitis, scarlet fever, andl erythema nodosum. Ten per cent. of the patients with a defi...

Acute rheumatic fever is a non-suppurative complication of Streptococcus pyogenes which only licks the joints, however bites the heart valves, particularly the mitral, aortic or both, rarely the tricuspid valve, resulting in valvular endothelial ulceration, collagen degeneration, neovascularization, interstitial calcification and fibrosis associated with lymphocytic infiltration [1]. Currently ...