OBJECTIVES Joint hypermobility (JH) or "ligamentous laxity" is felt to be an underlying risk factor for many types of musculoskeletal presentation in paediatrics, and joint hypermobility syndrome (JHS) describes such disorders where symptoms become chronic, often more generalized and associated with functional impairment. Clinical features are felt to have much in common with more severe disord...

It has been pointed out that immunosuppression with cytotoxic, nonsteroidal drugs is associated with the development of cytomeglovirus (CMV) infection after renal transplantation, and that without such immunosuppression infection may not occur (3). What is not known is whether immunosuppression alone, without other factors peculiar to the transplant recipient, can cause CMV infection. One appro...

BACKGROUND Juvenile idiopathic arthritis (JIA) is associated with significant morbidity in adulthood with at least one third of children continuing to have active inflammatory disease into their adult years and up to 60% of all patients continuing to have some limitation of their activities of daily living. A survey of service provision for these young people in the transition from paediatric t...