The purpose of the current study was to investigate whether peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 (Pin1) can interact with calpastatin (CAST) and regulate CAST/calpain2, under excessive glutamate conditions, and subsequently regulate necrosis in rat retinal neurons. Glutamate triggered CAST/calpain2-mediated necrosis regulation in primary cultured retinal neurons, as demonstrat...

Nodular cast iron insert will be used as the inner component of nuclear fuel disposal canister. The outer cover of the canister is copper tube of 50 mm nominal thickness. Nodular cast iron insert is cast around several steel channels, which also strengthen the structure. The mechanical properties of the cast iron insert will be tested according EN-1563 /1/. According the specifications 100% NDT...

Master moulds are used to cast copper anode moulds. These iron moulds are made of grey or nodular cast irons. According to desirable properties of ductile irons, it was expected that ductile cast iron ...

High density polyethylene (HDPE) films were produced using cast film extrusion process with different draw ratios, ranging from 16.9 to 148.8. Morphology, crystallinty and orientation state of crystalline and amorphous phases of the cast films were investigated using scanning electron microscopy (SEM), differential scanning calorimetry (DSC) and polarized Fourier transform infrared spectroscopy...

high density polyethylene (hdpe) films were produced using cast film extrusion process with different draw ratios, ranging from 16.9 to 148.8. morphology, crystallinty and orientation state of crystalline and amorphous phases of the cast films were investigated using scanning electron microscopy (sem), differential scanning calorimetry (dsc) and polarized fourier transform infrared spectroscopy...

In a natural environment, cast shadows abound. Objects cast shadows both upon themselves and upon background surfaces. Previous research on the perception of 3-D shape from cast shadows has only examined the informativeness of shadows cast upon flat background surfaces. In outdoor environments, however, background surfaces often possess significant curvature (large rocks, trees, hills, etc.), a...

Color cast defect detection of video image is challenging and of great importance in the field of video quality evaluation, and one of the difficulties therein is how to distinguish a dominant color (caused by a predominant color, such as an image in which blue sky is a basic tone) from an inherent cast (image presenting a cast due to imaging device failure or taken in a special environment, su...

BACKGROUND Calpain is activated following myocardial infarction and ablation of calpastatin (CAST), an endogenous inhibitor of calpains, promotes left ventricular remodeling after myocardial infarction (MI). The present study aimed to investigate the effect of transgenic over-expression of CAST on the post-infarction myocardial remodeling process. METHOD We established transgenic mice (TG) ub...

Calpastatin, an important protein used to regulate meat quality traits in animals, is encoded by the CAST gene. The aim of the present study was to clone the cDNA sequence of the CAST gene and detect the expression of CAST in the tissues of Cyprinus carpio. The cDNA of the C. carpio CAST gene, amplified using rapid amplification of cDNA ends PCR, is 2834 bp in length (accession No. JX275386), c...

BACKGROUND The scaphoid fractures account for 50%-80% of all carpal bone fractures in young individuals. Non-union of the fracture occurs in approximately 5%-10% of undisplaced scaphoid fractures. Current management varies significantly among different places and surgeons. OBJECTIVES The purpose of this review is to investigate the evidence of the effectiveness and safety of various treatment...