نتایج جستجو برای: rich plasma platelet rich fibrin chemokine cxcl12 cartilage knee
تعداد نتایج: 722480 فیلتر نتایج به سال:
Background: Platelet-rich plasma (PRP) has been advocated as one treatment for cartilage tissue regeneration. To date, several different platelet-rich formulations have been available, but a deep knowledge of their composition and mechanism of action in a specific clinical use is needed. The aim of this study was to investigate the effect of various PRP formulations on human chondrocytes in vitro.
BACKGROUND Periodontitis is characterized by the formation of true pockets, bone loss and attachment loss. Various techniques have been attempted in the past to truly regenerate the lost periodontal structures, albeit with variable outcome. In this evolution, the technique being tried out widely is the use of platelet rich concentrates, namely platelet-rich fibrin (PRF). CASE DESCRIPTION In t...
Abstract Purpose At present, autologous platelet-derived therapies such as platelet-rich plasma is widely used in the clinic, but allogeneic and xenogeneic are currently research stage, mainly due to their biocompatibility vivo. Platelet lysates depleted of antigens blood cells a potential solution for or applications. can successfully promote growth differentiation vitro, vivo data not yet ava...
Conclusion The platelet-rich plasmas failed to demonstrate significant benefits that justify the daily use, and the use of platelet-rich fibrin is limited to some very specific applications in which satisfactory results were achieved. Only a new simple, inexpensive and efficient technique such as the leucocyteand platelet-rich fibrin will continue to develop in oral and maxillofacial surgery in...
Fibrin, the coagulation end product, consolidates the platelet plug at sites of vascular injury and supports the recruitment of circulating platelets. In addition to integrin αIIbβ3, another as-yet-unidentified receptor is thought to mediate platelet interaction with fibrin. Platelet glycoprotein VI (GPVI) interacts with collagen and several other adhesive macromolecules. We evaluated the hypot...
BACKGROUND Platelet-rich plasma therapies for tendinopathy appear to provide moderate pain reduction. However, the biological mechanisms behind the observed clinical effects remain poorly characterized. QUESTIONS/PURPOSES The purpose of this study was to explore whether platelet-rich plasma modifies the inflammatory/angiogenic status of already inflamed tenocytes by examining (1) gene express...
Background: Platelet Rich Plasma (PRP) contains Growth Factors (GFs) and antiinflammatory agents with possibility of application in regeneration of damaged cartilage in the treatment of osteoarthritis (OA). In the most trials, three injections of PRP have been done but in this research we assessed the efficacy and safety of single injection of PRP in the management of OA. Methods: In th...
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