Left ventricular function was assessed in 14 patients with chronic aortic regurgitation by afterload elevation with angiotensin. Seven of 14 patients maintained their resting ejection fraction with angiotensin (group A), while the remaining seven experienced a decline of greater than 0.10 in ejection fraction (group B). Six of seven group A patients showed an appropriate rise in left ventricula...

In eight adult dogs the main pulmonary artery was constricted to elevate the right ventricular peak systolic pressure to 50% of the peak aortic pressure at rest. The response of the right ventricle was assessed immediately, at 30 minutes and at six months. The right ventricle responded to acute systolic loading by complete compensation. After 30 minutes there was a reduction in the right ventri...

We previously showed that the extent of infarction is virtually identical in patients with anterior and inferior infarction despite the more favorable prognosis associated with the latter. We postulated that the damage associated with inferior infarction is shared by both ventricles, thereby causing less hemodynamic impairment than anterior infarction, which involves only the left ventricle. To...

We previously showed that the extent of infarction is virtually identical in patients with anterior and inferior infarction despite the more favorable prognosis associated with the latter. We postulated that the damage associated with inferior infarction is shared by both ventricles, thereby causing less hemodynamic impairment than anterior infarction, which involves only the left ventricle. To...

We previously showed that the extent of infarction is virtually identical in patients with anterior and inferior infarction despite the more favorable prognosis associated with the latter. We postulated that the damage associated with inferior infarction is shared by both ventricles, thereby causing less hemodynamic impairment than anterior infarction, which involves only the left ventricle. To...

Objective: To assess with magnetic resonance imaging (MRI) cardiovascular function in response to exercise in patients after atrial correction of transposition of the great arteries (TGA). Methods: Cardiac function at rest and during submaximal exercise was assessed with MRI in 27 patients with TGA (mean (SD) age 26 (5) years) late (23 (2) years) after atrial correction and in 14 control partic...

Peak aortic blood acceleration is recognized to be a sensitive index of global left ventricular performance. In the present study peak acceleration was assessed noninvasively in patients with a continuous-wave Doppler velocity meter. Peak aortic blood velocity and peak blood acceleration were measured by placing the ultrasonic transducer at the suprastemal notch. Measurements were obtained in 3...

Peak aortic blood acceleration is recognized to be a sensitive index of global left ventricular performance. In the present study peak acceleration was assessed noninvasively in patients with a continuous-wave Doppler velocity meter. Peak aortic blood velocity and peak blood acceleration were measured by placing the ultrasonic transducer at the suprastemal notch. Measurements were obtained in 3...