Rosmarinic acid (RA) is an ester of caffeic acid and 3, 4-dihydroxyphenyllacticacid. It is commonly found in Coleus blumei, Salvia officinalis, Melissa officinalis and Rosmarinus officinalis. The biosynthesis of RA starts with precursor molecules L-phenylalanine and L-tyrosine. Simulation of RA biosynthetic pathway was done using Gepasi Software, includes the reaction kinetics of each step of t...

The aim of this study was to evaluate the safety, tolerability and pharmacokinetics of single dose of Melissa officinalis extract which contained rosmarinic acid, including food-effects in healthy individuals. A total of eleven healthy individuals were randomly assigned to treatment arms in the two studies [Study 1 (fasted state) and Study 2 (fed state)]. Rosmarinic acid in serum was measured b...

The aim of this work is to assess the morphological characteristics and parameters of biomass production, such as fresh and dry matter weight (FMW and DMW, g/plant), yield of dry matter (YDM) in terms of ton/ha, essential oil content (EOC, mL/100 g) and yield of essential oils (YEO) expressed as L/ha of the following plants Salvia verbenaca, Salvia argentea, Salvia lavandulifolia, Salvia praten...

We evaluate the sedative and hypnotic activities of the methanolic and aqueous extract of Lavandula officinalis L. on central nervous system (CNS). In this study, the effect of the methanolic and aqueous extracts of this plant was investigated in a battery of behavioural models in mice. Stems and flowers of Lavandula officinalis L. have several therapeutic applications in folk medicine in curin...

Calendula officinalis L. has been largely known for its topical anti-inflammatory properties; however, there are no experimental evidences about its antiphlogistic effect at the gastric level. To investigate whether marigold might exert an activity against gastric inflammation, a CH2Cl2 extract obtained from C. officinalis flowers was evaluated in vitro on the NF-κB pathway. The lipophilic extr...

Kombucha is a fermented tea beverage which is traditionally prepared by fermenting sweetened black or green tea (Camellia sinensis L.) with symbiotic consortium of bacteria and yeasts (SCOBY). In this study, lemon balm (Melissa officinalis L.) was used as the only nitrogen source for kombucha fermentation. During the seven-day fermentation process, pH value, titratable acidity (TA), total pheno...

Model studies of the influence lectin-containing extracts medicinal plants St. John's wort (Hypericum perforatum L.), common yarrow (Achillea millefolium marigold (Calendula officinalis L.) and dwarf evergreen (Helichrysum arenarium (L.) Moench.) on growth development wheat, oat, barley rye at beginning their ontogenesis. They testify to specificity action in relation model objects, which is pr...

Original Article Thymus vulgaris Melissa officinalis Salvia officinalis Anchusa officinalis Coleus blumei O. sanctum

ABSTRACT: Lemon balm, Melissa officinalis, is a member of the mint family that is native to Europe. Its use as a medicinal herb dates from the Middle Ages, and it is very well known for its ability to reduce stress and anxiety, promote sleep, improve appetite, and ease pain and discomfort associated with digestion and Mentha longifolia (Lamiaceae), commonly known as wild mint, Various biologica...

Valeriana Officinalis L. e a Hypericum Cavernicola B. SM., são espécies que apresentam uso medicinal para dores de cabeça anti-inflamatório. Plantas medicinais têm sido propagadas por métodos micropropagação é propagação clonal um genótipo selecionado in vitro. O objetivo do trabalho foi avaliar os efeitos das diferentes concentrações meio cultura MS BAP na Cavernicola. realizado no Laboratório...