background: astrocytes, which comprise ~90% of overall brain mass, are involved in brain immunity. these cells represent the non-professional class of cns-resident apcs and may promote or inhibit cns inflammation depending on the cytokines they secrete. il-10 family of cytokines and their receptors, il-20r1 and il-20r2, may have a role in shifting astrocytes to a neuroprotective or neurodegener...

The incidence of cardiovascular disease (CVD) is increased in the endocrine-metabolic condition polycystic ovary syndrome (PCOS) which impacts 10-15% females. mechanisms cardiac dysfunction PCOS related to hyperandrogenemia, and androgen receptor (AR) estrogen (ER) activation remain unclear. aim this study was investigate effect treatment on AR ER activation, fatty acid metabolism function a PC...

Background: Corona virus disease 2019 has taken a huge toll over health infrastructure and care all across the world. This article depicts our experience of COVID-19 in pregnant women analyses maternal neonatal outcome same first second wave this pandemic. Aim objectives study were to compare demographic characteristics, presenting features fetomaternal COVID positive v/s tertiary hospital.Meth...

Background: The estimation of risk factors for death can help in modifying the screening, treatment strategy and saving valuable lives. published data about this topic from India is scarce. We aim to explore in-hospital deaths COVID-19 patients.Methods: This was a hospital-based cross-sectional study. All patients positive on reverse transcriptase–polymerase chain reaction (RTPCR) test who were...

Background: Coronavirus disease 2019 (COVID-19) is a global health issue. Healthcare workers (HCWs) are especially vulnerable to infection by SARS-CoV-2. The present study was conducted determine the proportion of HCWs infected with COVID 19 in tertiary care centre emphasis on epidemiological and clinical aspectMethods: (symptomatic asymptomatic contacts) who tested positive for COVID-19 SARS-C...

Background- The current outbreak of viral pneumonia, caused by novel coronavirus SARS-CoV-2, is the focus worldwide attention.Based on their mechanism action and demonstrated utility in chronic inflammatory conditions early feasibility studies COVID-19, there a strong case for TNF inhibitor use COVID-19. Objectives-To find out Outcome covid 19 patients treated with without monoclonal antibody –...

Background: Infertility affects 15% of couples around the world. Male factor accounts for 40-50% of conjugal infertility. cAMP responsive element modulator (CREM) is a key factor in the regulation of the expression of number of postmeiotic genes that control spermatogenesis. Aloe vera is a medicinal plant used to treat several diseases. The purpose of this study was to investigate effects of Al...

Background: The novel human corona virus disease (COVID-19) is the fifth documented pandemic in history since 1918 flu pandemic. Along with other clinical features, loss of smell has been reported as a prime symptom COVID-19 positive patients. aim to determine frequency infection patients who came sudden development smell. Materials & Methods: This study was done Uttara Crescent Hospital, p...

Abstract Background The Omicron surge caused a significant strain on the healthcare system, particularly as it relates to worker (HCW) infections. Occult infection transmission from HCWs patients is an important area upon which control programs can continue improve. Methods We conducted retrospective chart review of 9 immunocompromised solid organ transplant service who were exposed highly infe...