The AML1 gene, situated in 21q22, is often rearranged in acute leukemias through t(8;21) translocation, t(12;21) translocation, or less often t(3;21) translocation. Recently, point mutations in the Runt domain of the AML1 gene have also been reported in leukemia patients. Observations for mutations of the Runt domain of the AML1 gene in bone marrow cells were made in 300 patients, including 131...

In this article we discuss discourses of white mobility in reality television, a genre whose problematic post-racial and neoliberal have long been exposed. Moving beyond the widely researched Anglophone media landscapes, interrogate discursive construction mobilities Swedish romance show Bonde Söker Fru – Jorden Runt (TV4, 2019–2020) [Farmer Seeks Wife Around World] where North-to-South migrant...

This case describes a young man with an unusual cause of severe osteoporosis and markedly deranged bone microarchitecture resulting in multiple fractures. A potentially pathogenic germline variant the runt-related transcription factor 1 (RUNX1) gene was discovered by focused 51-gene myeloid malignancy panel during investigation for his unexplained normochromic normocytic anemia. Further bone-sp...

that leads to sequential expression of other transcription factors and of phenotype-specific genes (Rawls and Department of Bone Biology and Osteoporosis Research Olson, 1997). Homology searches for HLH factors that play a similar role in adipocyte, osteoblast, or chon-Merck Research Laboratories West Point, Pennsylvania 19486 droblast differentiation have not been successful (negative data are...

The AML1 gene, situated in 21q22, is often rearranged in acute leukemias through t(8;21) translocation, t(12;21) translocation, or less often t(3;21) translocation. Recently, point mutations in the Runt domain of the AML1 gene have also been reported in leukemia patients. Observations for mutations of the Runt domain of the AML1 gene in bone marrow cells were made in 300 patients, including 131...

The main purpose of this review is to discuss associations between within-litter variation in birth weight, and preweaning survival and postnatal growth in the pig, as the basis for suggesting that the developmental competence of pigs born, as well as the size of the litter, need critical consideration. Extremes of intrauterine growth retardation (IUGR) occur within a discrete subset of fetuses...