PROCOGNATE is a database of protein cognate ligands for the domains in enzyme structures as described by CATH, SCOP and Pfam, and is available as an interactive website or a flat file. This article gives an overview of the database and its generation and presents a new website front end, as well as recent increased coverage in our dataset via inclusion of Pfam domains. We also describe navigati...

This article presents a historical review of the protein structure classification database CATH. Together with the SCOP database, CATH remains comprehensive and reasonably up-to-date with the now more than 100,000 protein structures in the PDB. We review the expansion of the CATH and SCOP resources to capture predicted domain structures in the genome sequence data and to provide information on ...

the effects of tilia plathphyllos scop. in a nervous disorder, including seizure was reported in traditional literatures. in the present investigation, the effects of methanolic extract of t. plathyphyllos on seizure induced by picrotoxin and pentylentetrazole were studied in mice. in this experimental study, groups of 5 animals pretreated with doses of 100, 200 and 300 mg/kg of methanolic extr...

The paper uses the SCOP theory of concepts to model the role of environmental context on three levels of entrepreneurial opportunity: idea generation, idea development, and entrepreneurial decision. The role of contextual-fit in the generation and development of ideas is modeled as the collapse of their superposition state into one of the potential states that composes this superposition. The p...

Objective Diabetes mellitus is manifested by hyperglycaemia. Different treatments such as diets and drugs are recommended for diabetes control. For various reasons in recent years traditional plant (herbal) therapies as prescribed by indigenous systems of medicine with different mechanisms have commonly been used. The digestive enzymes such as alpha glucosidase are among these herbal remedies....