Introduction: Trypanosoma cruzi is the agent of Chagas’ disease and affects approximately 6-8 million people worldwide. The search for new anti-T. drugs are relevant because only two exist actually. objective this study was to investigate effect extracts from seeds Lonchocarpus cultratus on T. cruzi, its cytotoxicity as well elucidate chemical profile.
 Methodology: characterization done u...

Sarcocystis neurona is the most common cause of Equine Protozoal Myeloencephalitis (EPM), affecting 0.5-1% horses in the United States during their lifetimes. The objective of this study was to evaluate the equine immune responses in an experimentally induced Sarcocystis neurona infection model. Neurologic parameters were recorded prior to and throughout the 70-day study by blinded investigator...

Sarcocystis neurona was isolated from the brain of a juvenile, male southern sea otter (Enhydra lutris nereis) suffering from CNS disease. Schizonts and merozoites in tissue sections of the otter's brain reacted with anti-S. neurona antiserum immunohistochemically. Development in cell culture was by endopolyogeny and mature schizonts were first observed at 3 days postinoculation. PCR of merozoi...

ABSTRACT: Cattle are considered intermediate hosts of Sarcocystis, which can cause clinical signs and lower performance in the acute phase infection. Sarcocystis spp. usually not visible to naked eye during post mortem inspection. Moreover, fresh microscopic examination transmission electron microscopy techniques difficult apply large samples. Therefore, extensive studies on infection cattle us...

Acquisition of detailed knowledge of the structure and evolution of Trypanosoma cruzi populations is essential for control of Chagas disease. We profiled 75 strains of the parasite with five nuclear microsatellite loci, 24Salpha RNA genes, and sequence polymorphisms in the mitochondrial cytochrome oxidase subunit II gene. We also used sequences available in GenBank for the mitochondrial genes c...

The influence of the number of sporocysts in the inoculum of Sarcocystis falcatula on the morphology of the sarcocysts has not been reported in the literature. To determine if there is a relationship, different number of sporocysts were inoculated orally into wild-caught cowbirds. After 14 weeks, the cowbirds were euthanised and muscle tissue was examined grossly and by histologic sections. Sar...

Auditory hallucinations in the population: what do they mean and what should we do about them? Citation Kelleher I. Auditory hallucinations in the population: what do they mean and what should we do about them? Acta Psychiatrica Scandinavica. 2016;134(1):3-5.

Toxoplasma gondii, Neospora spp., Sarcocystis spp., Hammondia spp. and Besnoitia besnoiti are genetically related cyst-forming coccidia. Serology is frequently used for the identification of T. gondii, Neospora spp. and B. besnoiti-exposed individuals. Serologic cross-reactions occur in different tests among animals infected with T. gondii and H. hammondi, as well as among animals infected by T...

Clinical and parasitological traits of Sarcocystis miescheriana differ in Pietrain and Meishan pigs. For further description and characterization of the genetic basis of this variation a F(2) family based on Pietrain boars and Meishan sows as founders was generated. One hundred and thirty-nine F(2) pigs were challenged orally at an age of 100 days with 50,000 sporozysts to produce the typical c...

The population genetics and systematics of most coccidians remain poorly defined despite their impact on human and veterinary health. Non-recombinant parasite clones characterized by distinct transmission and pathogenesis traits persist in the coccidian Toxoplasma gondii despite opportunities for sexual recombination. In order to determine whether this may be generally true for tissue-cyst form...