primary cardiac sarcomas are rare clinical entities with an incidence rate of 0.0001% in collected autopsy series and are regarded as very aggressive tumors. we herein describe a 21-year-old woman presenting with syncope, dyspnea, and abdominal distention. she suffered from massive ascites, plural effusion, and liver congestion demonstrated by abdominal sonography and chest x-ray. transthoracic...

hereby we report a case of well-differentiated intraosseous osteosarcoma in the sacrum. a 32-year-old woman was admitted to our hospital with a low echo-level mass in the pelvis searched by ultrasound in a routine physical examination. radiographically, the mass was misdiagnosed as a benign bony tumor originating from the sacrum. the tumor was completely resected and pathological diagnosis was ...

background & aim: malignant fibrous histiocytoma (mfh), is the most common soft tissue sarcoma in adults and is frequently seen is elderly. this lesion is so rare in bones and if seen, is common in long bones and the incidence of the lesion in maxillofacial bones is uncommon. in addition, maxilla is an unusual site for malignant fibrous histiocytoma (mfh). the aim of this article was to report ...

myeloid sarcoma (ms) is a tumor mass consisting of myeloblast with or without maturation occurring at an anatomical site other than the bone marrow. incidence of ms ranges from 1-9% and is most commonly misdiagnosed as non hodgkins lymphoma or poorly differentiated carcinoma. ms can occur in various sites but nasal cavity involvement is rare. here we report acaseof ms presenting as nasal polyp ...

kaposiform hemangioendothelioma is an aggressive endothelial-derived spindle cell neoplasm that occurs nearly exclusively during childhood and teenage years. the lesion grows rapidly and is often associated with kasabach-merritt syndrome. in this study a 24 days old male neonate who presented with an ill-defined deeply situated violaceous mass on his left arm is described. he had also anemia an...

myeloid sarcoma of female breast is a rare presentation of acute myeloid leukemia (aml). the tumor mass may precede or occur concurrently with aml, cml, myeloproliferative disorders, and/or myelodysplastic syndromes. histologically, it looks like a large cell lymphoma and can be misdiagnosed. a case referred as a suspected case of large cell lymphoma. initial morphological study with convention...

background: kaposi’s sarcoma is a vascular malignancy, which frequently occurs among immunocompromised individuals such as transplant recipients and patients with acquired immunodeficiency syndrome. human herpesvirus 8 (hhv-8) is considered the etiological agent of all forms of kaposi’s sarcoma. though some seroepidemiological studies conducted on the prevalence of hhv-8 in iran, there are insu...

Current therapies for sarcomas are often inadequate. This study sought to identify actionable gene targets by selective targeting of the molecular networks that support sarcoma cell proliferation. Silencing of asparagine synthetase (ASNS), an amidotransferase that converts aspartate into asparagine, produced the strongest inhibitory effect on sarcoma growth in a functional genomic screen of mou...

Background: Synovial sarcoma is one of the rarest soft tissue tumor with a high grade malignancy. Primary synovial chest wall rare.
 Presentation case: A 65-year-old woman presented history left upper mass previously operated 9 months ago. The pathological report was sarcoma. Computed tomography done and revealed RT anterior infraclavicular cystic solid lesions measuring 8.5 *3.5*4 cm.&#x0...

In 1935 Roberts and Roberts reported the occurrence of osteogenic sarcoma in nonidentical siblings (one brother and two sisters) with no previous chronic bone disorder. In this report fibrosarcoma and osteogenic sarcoma were included : one tumour was diagnosed as fibrosarcoma, one as sclerosing osteogenic sarcoma, and one as round-cell osteogenic sarcoma. A year later the occurrence of osteogen...