Androgen treatment can enhance the size and strength of muscle. However, the mechanisms of androgen action in skeletal muscle are poorly understood. This review discusses potential mechanisms by which androgens regulate satellite cell activation and function. Studies have demonstrated that androgen administration increases satellite cell numbers in animals and humans in a dose–dependent manner....

A purification scheme for satellite DNA containing chromatin from mouse liver has been developed. It is based on the highly condensed state of the satellite chromatin and also takes advantage of its resistance to digestion by certain restriction nucleases. Nuclei are first treated with micrococcal nuclease and the satellite chromatin enriched 3-5 fold by extraction of the digested nuclei under...

Received Jul 5, 2014 Revised Nov 11, 2014 Accepted Nov 22, 2014 In this paper, an algorithm was presented to control the satellite attitude in orbit in order to reduce the fuel consumption and increase longevity of satellite. Because of proper operation and simplicity, fuzzy controller was used to save fuel and analyze the uncertainty and nonlinearities of satellite control system. The presente...

IN THE NEWS FOCUS STORY “WEATHER forecasts slowly clearing up” (9 November, p. 734), R. Kerr nicely summarizes how the growing improvement in prediction is coming from a focus on “more computer power, the assimilation of radar observations, and more physically realistic models.” He emphasizes that better assimilation of satellite data is a key element of improved forecasting. Unfortunately, the...

INTRODUCTION Muscle stem cells termed satellite cells are essential for muscle regeneration. A central question in many neuromuscular disorders is why satellite cells are unable to prevent progressive muscle wasting. We have analyzed muscle fiber pathology and the satellite cell response in Pompe disease, a metabolic myopathy caused by acid alpha-glucosidase deficiency and lysosomal glycogen ac...

We have studied the origin of muscle satellite cells in embryos of Xenopus laevis. Fate mapping at the open neural plate stage was carried out using orthotopic grafts from transgenic embryos expressing GFP. This shows that most satellite cells originate from the dorsolateral plate rather than from the paraxial mesoderm. Specification studies were made by isolation of explants from the paraxial ...

Aiming at the requirement of the autonomous time synchronization in BeiDou Navigation Satellite System (BDS), an algorithm for inter-satellite autonomous time synchronization and ranging is proposed. Based on the establishment of the inter-satellite link length model of the BDS, a series of simulation has been carried out through the use of STK (Satellite Tool Kit), which includes the simulatio...

Satellite cells are well known as a postnatal skeletal muscle stem cell reservoir that under injury conditions participate in repair. However, mechanisms controlling satellite cell quiescence and activation are the topic of ongoing inquiry by many laboratories. In this study, we investigated whether loss of the cell cycle regulatory factor, pRb, is associated with the re-entry of quiescent sate...

Satellite services (e.g. Internet-over-Satellite or GPS) are getting more and more important in our lives, whereby the operational area is still growing. To guarantee those services, reliable simulation tools are necessary to scale and validate actual and future satellite systems. Therefore, this paper gives an overview about development, functionalities and benefit of a satellite simulation fr...

Muscle wasting in chronic kidney disease (CKD) begins with impaired insulin/IGF-1 signaling, causing abnormal protein metabolism. In certain models of muscle atrophy, reduced satellite cell function contributes to atrophy, but how CKD affects satellite cell function is unknown. Here, we found that isolated satellite cells from mice with CKD had less MyoD, the master switch of satellite cell act...