For the paradigmatic case of H(2) dissociation, we compare state-of-the-art many-body perturbation theory in the GW approximation and density-functional theory in the exact-exchange plus random-phase approximation (RPA) for the correlation energy. For an unbiased comparison and to prevent spurious starting point effects, both approaches are iterated to full self-consistency (i.e., sc-RPA and sc...

Stochastic computing (SC) is an emerging computing technique that promises high density, low power, and error tolerant solutions. In SC, values are encoded as unary bitstreams and SC arithmetic circuits operate on one or more bitstreams. In many cases, the input bitstreams must be correlated or uncorrelated for SC arithmetic to produce accurate results. As a result, a key challenge for designin...

In prion diseases, abnormal prion protein (PrP(Sc)) is considered as the main component of the infectious agent. Delineation of PrP(Sc) conformation is expected to be a critical factor in understanding properties of prions. However, practical methods to differentiate between conformers of PrP(Sc) are inadequate. Here, we used two PrP(Sc)-specific monoclonal antibodies (mAbs), 3B7 and 3H6, and f...

The conversion of normal cellular prion protein to disease-associated prion protein (PrP(Sc)) is a fundamental component of prion disease pathogenesis. The molecular mechanisms contributing to prion conversion and the impact of PrP(Sc) accumulation on cellular biology are not fully understood. To further define the molecular changes associated with PrP(Sc) accumulation in cultured cells, the tr...

OBJECTIVE To investigate what happens to the serum creatinine (SC) levels of people with initial mild elevations in SC; whether a stable, non-progressive elevation in SC level is the most common scenario; how common a progressive increase in SC is among primary care patients; and how often primary care patients with substantial elevations in SC (>300 micromol/L) progress to end-stage renal dise...

•Sebaceous carcinoma (SC) is rare with only nine cases reported in the literature.•Extraocular SC likely has similar prognosis to ocular SC.•Reporting of vulvar SC should include detailed pathologic information so that risk factor associations can be made.

Cast, coarse-grained Al-Sc alloys are interesting candidates for high temperature, creepresistant applications due to the formation of a high number density of nanometer sized Al3Sc precipitates [1]. Upon addition of Yb to Al-Sc alloys, Yb replaces the Sc forming Al3(Sc1-xYbx) precipitates (L12 structure) [2]. The resulting alloys have higher creep resistance due to the larger lattice parameter...

As today’s supply chain (SC) networks are globalized complex systems planning and optimizing SC processes is harder than ever. Unexpected deviations and disruptions can lead to devastating and far-reaching consequences. Hence, the management of SC risk (SCR) is of fundamental importance. The literature on SCR is, however, mostly of anecdotic nature; only few authors present empirical research. ...