Chronic inflammation is associated with various chronic illnesses including immunity disorders, cancer, neurodegeneration, and vascular diseases. Iridoids are compounds with anti-inflammatory properties. However their anti-inflammatory mechanism remains unclear. Here, we report that scropolioside B, isolated from a Tibetan medicine (Scrophularia dentata Royle ex Benth.), blocked expressions of ...

Chemical composition of the essential oil obtained from the aerial parts of Scrophularia amplexicaulis Benth. was analyzed, for the first time, by the gas chromatography/mass spectrometry (GC-MS) and gas chromatography/flame ionization detection (GC-FID). A total yield of 3 mg of essential oil per100 g of plant dry mass was obtained, and 27 compounds were identified, representing 97.7% of total...

background and objectives:scrophularia variegata m. beib. (scrophulariaceae) is a medicinal plant, used for various inflammatory diseases in iranian traditional medicine. in the present study, we evaluated the immune modulation and antioxidant effects of the hydroalcoholic extract of s.  variegata. methods: the splenocytes were harvested from the spleen of balb/c mice and were cultured. the spl...

the overall goal of this review is to discuss the potential efficacy of herbal treatments. plants are considered among the main sources of biologically active chemicals. plant based drugs usage in our past decay became very renowned due to their fewer side effects and being less expensive than chemical ones. recently, more abrupt tendency in this field has been increased. furthermore, advances ...

Background: Myocardial infarction (MI) is the leading cause of death among cardiovascular diseases. Reperfusion, most harmful phase, accompanied by inflammatory, oxidative, and apoptotic cascades in cardiomyocytes, impairing hemodynamic histologic status cardiac tissue. The Scrophularia genus well known for cardioprotective effects its species, showing beneficial impacts on blood pressure arrhy...