We investigated the capacity of newborn rats to excrete an acute potassium load to understand the development of a renal potassium excretion system. Three groups of the rats (7-14 d) were used to collect urine periodically over 6 h after oral infusion of potassium: control (no potassium loading) and low- and high-potassium-loaded rats. In the low-potassium-loaded group, infused with about 0.6 m...

Telomeres are ribonucleoprotein structures forming a protective buffer at the ends of chromosomes. They preserve integrity genetic material during cell cycle. Replicative telomere erosion can be compensated by telomerase.

Of the nineteen cases of Gramoxone poisoning treated at the Medical Unit, Toa Payoh Hospital, three survived. The clinical data of these survivors is presented. The maximal ingested dose compatible with life in the present series is twenty millilitresof Grammoxonewhile the excretion rate of paraquat in urine in a non -fatal case is 0.92 mg/hr in the first 24 hours. In the follow-up of these sur...

NB-003 and NB-003 gel formulations are oil-in-water nanoemulsions designed for use in bacterial infections. In vitro susceptibility of Propionibacterium acnes to NB-003 formulations and comparator drugs was evaluated. Both NB-003 formulations were bactericidal against all P. acnes isolates, including those that were erythromycin, clindamycin, and/or tetracycline resistant. In the absence of seb...

INTRODUCTION Numerous plant products described in the scientific literature show distinct activities on the skin, such as moisturizing, antioxidant, sunscreen, anti-acne and depigmentation. AIM The main objective of this study was to compare the effectiveness of emulsion formulations containing plant extracts (Hippophae rhamnoides and Cassia fistula) and placebo (without plant extracts) on ac...

BACKGROUND Measuring the 24-hour urine protein ≥300 mg is the standard threshold value for diagnosis of preeclampsia. OBJECTIVE This study was intended to determine if a patient's 4-hour urine protein correlate with the 24-hour value for diagnosis of preeclampsia. MATERIALS AND METHODS This was a cross sectional study performed on 84 women with suspected preeclampsia due to positive urinary...