Deciding when to operate on a patient with chronic aortic regurgitation may be extremely difficult. The timing of surgery requires consideration of the etiology and pathophysiology of the aortic regurgitation, because aortic valve replacement carries morbidity and mortality that must be weighed against the potential problems of continued medical management. Guidelines for the use of surgery in ...

Currently competitive world outsourcing is one of the important strategies used by modern enterprises. Contractor selection is characterized as a multi-criteria decision-making problem that comprises tangible and intangible factors. Previous contractor selection techniques do not consider strategic perspective. This paper applied quantified SWOT in the context of contractor selection under a fu...

in recent years, supply chain management has developed into one of the most critical strategies for achieving competitive advantage in different industries and the supplier selection process has increasingly been distinguished as an important and vital decision in supply chain management of manufacturing and service industries. on the other hand, with so many suppliers having different capabili...

Rapid and efficient cooling is the most important therapeutic objective in patients with heat stroke (HS). This article reviews the mechanism of action and rationale for the use of dantrolene as a potential supportive cooling method in the treatment of HS. Relevant studies were included to support discussion of the role of dantrolene for the treatment of HS. In some studies dantrolene was shown...

Atherosclerosis and cancer are the leading causes of death in industrialized society. Although atherosclerosis has been considered to be multi-factorial disease in which genetic, environmental, and other factors have been implicated, the gaps remain in our knowledge of the etiopathogenesis as well as features of atherosclerosis. However, Numerous data suggested that the some characteristics of ...

The last decade has seen many trials with antioxidants in patients with cardiovascular disease, with equivocal results. One possible explanation for the disappointing findings is the lack of identification criteria of patients who are potential candidates for antioxidant treatment. Several studies have been carried out in patients at risk of cardiovascular disease, indicating that enhanced oxid...

Qualitative and quantitative serum human chorionic gonadotropin (hCG) tests are used to diagnose pregnancy. We assessed physicians' perceptions and compared turnaround times (TATs) and performance characteristics of both tests. We surveyed 1,058 physicians about their perceptions of hCG tests. Seven months of TAT data were analyzed. hCG was measured in all qualitative samples. Pregnancy status ...

The intercellular lipids in the stratum corneum form structures composed of ordered phases with orthorhombic and hexagonal hydrocarbon-chain packing structures and, in addition, a structure composed of a disordered fluid phase. Although the fluid phase plays an important role in percutaneous penetration, little attention has been paid to it in the literature thus far. Recently, a method to esti...