Opiate dependence and withdrawal have long been hypothesized to enhance the reinforcing effects of opiates; however, opiate agonist self-administration in these states has yet to be systematically assessed. To address this issue, the reinforcing property of the short-acting -opioid agonist, remifentanil, was assessed in morphine-dependent (MD), morphine-dependent and -withdrawn (MW), and nondep...

BACKGROUND The Dependence Scale measures the amount of assistance patients with dementia require in performing daily activities. Validity and reliability of this scale have been demonstrated, but the progression throughout long periods in patients with Alzheimer disease (AD) has not previously been examined. OBJECTIVE To determine the longitudinal course of patient dependence in a cohort of p...

Learner autonomy has become the area of interest by many researchers of foreign language learning in the recent years. However, few studies have been done concerning the case of Kurdish learners` autonomy in learning languages. For this reason, the current study addresses this gap. It intends to investigate to what extent Kurdish learners are autonomous in learning English language. The study i...

background: rhinoplasty is the most common cosmetic surgery which has been dramatically increasing in iran. currently, iran is ranked the first in the world in rhinoplasty. in the present study, we aimed to assess the character and temperament traits of the applicants referred to rhinoplasty surgeons in shiraz, southwest iran in 2015. methods: in this cross-sectional study, we recruited 500 par...

Although lisdexamfetamine is used as a recreational drug, little research exists regarding its potential for dependence or its precise mechanisms of action. This study aims to evaluate the psychoactivity and dependence profile of lisdexamfetamine using conditioned place preference and self-administration paradigms in rodents. Additionally, biochemical techniques are used to assess alterations i...

We investigate the electronic transport through a single-level quantum-dot which is capacitively coupled to a charge-qubit. By employing the method of nonequilibrium Green's functions, we calculate the electric current through quantum dot at finite bias voltages. The Green's functions and self-energies of the system are calculated perturbatively and self-consistently to the second order of inte...

conclusions metacognitive regulation strategies are more considerable prediction than emotional regulation strategies in sd group than in ad group. individuals with ad use alcohol as a means of both cognitive and emotional regulation strategy. patients and methods according to dsm-iv tr criteria, 45 patients with alcohol dependence (ad), 44 patients with substance dependence (sd), and 43 volunt...

conclusions opium was not identified as a risk factor of ischemic stroke. a more extended survey considering further confounding factors is recommended. background one of the supposed risk factors of ischemic stroke is opium addiction, while the researches about its prevalence among patients with stroke are limited. objectives the aim of this study was comparing the prevalence of opium addictio...

BACKGROUND Emotional and interpersonal impairments associated with alcohol-dependence have been recently explored, but the distorted cognitive representations underlying these deficits remain poorly understood. The present study aims at exploring the presence of maladaptive social self-beliefs among alcohol-dependent individuals, as these biased self-beliefs have been recently shown to play a c...