Abstract Objective Thalassemia major is a severe transfusion-dependent anemia that needs iron chalation therapy to remove iron overload. The objectives of the present study were to assess the iron overload liver response to inulin of chicory supplementation by evaluating the serum ferritin and liver enzymes. Methods Among 70 beta thalassemia patients, 50 were selected for chelating therapy ...

1. Ferritin has been partially purified from the serum of patients with idiopathic haemochromatosis. 2. Incubation with neuraminidase of this partially purified serum ferritin eliminated much of the microheterogeneity of the protein so that only ferritin of isoelectric point approximately 5.8 was present. 3. There was no change in the total amount of ferritin present (measured immunologically) ...

Background: Iron deficiency is the most common single-nutrient deficiency disease in the world and is a major concern for about 15% of the world population.  It has been shown that iron deficiency may affect thyroid hormones. Objective: To determine thyroid hormone status in iron deficient adolescent girls. Methods: A cross-sectional study was carried out in Lar Province and its’ vicinity in So...

BACKGROUND In clinical medicine, ferritin is predominantly utilized as a serum marker of total body iron stores. In cases of iron deficiency and overload, serum ferritin serves a critical role in both diagnosis and management. Elevated serum and tissue ferritin are linked to coronary artery disease, malignancy, and poor outcomes following stem cell transplantation. Ferritin is directly implicat...

INTRODUCTION Iron parameters like serum ferritin and iron saturation are routinely used in diagnosing iron deficiency. However, these tests are influenced by many factors. We aimed to review the accuracy of iron parameters among inpatients in an acute care hospital. MATERIALS AND METHODS From October 1997 to April 2002, bone marrow aspirate samples from patients on whom concurrent iron studie...

BACKGROUND Low serum ferritin levels signify low iron stores and this could predispose to iron deficiency anemia. OBJECTIVE To determine the rate and predictors of low serum ferritin levels during the puerperium in Enugu, Southeast Nigeria. STUDY DESIGN A hospital-based prospective longitudinal study involving parturient women who delivered singleton fetuses at term. Venous blood samples we...

UNLABELLED In addition to its important role as marker of iron stores, serum ferritin is a marker of systemic inflammation, and obesity has been associated with chronic inflammation. OBJECTIVE To verify, six months after surgery, the effect of bariatric surgery on the serum ferritin of women who were hypertensive, diabetic, or comorbidity free before surgery. SAMPLE AND METHODS This retrosp...

BACKGROUND Diagnosis and treatment of iron deficiency anemia in older subjects improves their quality of life. Serum ferritin as a marker of iron stores is an acute phase protein. In older subjects who usually have many concomitant chronic medical conditions, serum ferritin may increase in response to inflammatory processes irrespective of iron stores. This study was performed to determine the ...

AIM To study the levels of serum ferritin in patients of renal cell carcinoma (RCC). PATIENTS AND METHODS Serum ferritin levels were measured preoperatively in 32 patients with radiological evidence of RCC using an enzyme immunoassay. The largest diameter of the primary tumor was measured in the pathological specimens in patients undergoing radical nephrectomy while in patients with non-opera...