Acute phase proteins play a significant role in anemia of chronic disease and thought to be beneficial in maintain homeostasis. In both the condition, anemia of chronic disease as well as iron deficiency anemia alteration in iron homeostasis takes place. The study includes patients of pulmonary tuberculosis patients (ACD), Iron deficiency anemia (IDA) patients and control subjects. Serum CRP, S...

To evaluate the serum concentrations of haptoglobin (Hp) and serum amyloid A (SAA) in water buffaloes with abomasal ulcers, the abomasums of 100 randomly selected water buffaloes were examined after slaughter. Type I abomasal ulcers were found in 56 out of 100 buffaloes. Serum concentrations of Hp and SAA were measured. There was no significant difference between affected and non-affected buffa...

Abraham (1) and Schutt (2), employing the method of continuous polyacrylamide electrophoresis for the sepa^ ration of serum proteins, found abnormal variations of haptoglobin levels together with those of transferrin (these proteins being a2and j3-globulins respectively), which gave a good indication for an early diagnosis of bronchial neoplasms. These authors reported (1,2) that in patients wi...

The effect of dietary restriction on the expression of retroviral envelope glycoprotein, gp70, and the formation of gp70-anti gp70 immune complexes was investigated in lupus-prone NZB x NZW F1 hybrid mice. Restricting total calorie intake from the usual 20 to only 10 calories per day after weaning markedly reduced serum levels of both free and antibody-complexed gp70, prevented renal disease, a...

preterm birth means the birth before thirty seven week of pregnancy that causes a lot of complications for the baby. variety factors are suggested to be involved in disease. in this study, we decided to evaluate haptoglobin (hp) phenotypes association with clinical features of patients suffered from premature delivery to understand better the possible correlation of genetic and clinical feature...

Human haptoglobin, the serum haemoglobinbinding protein, can be differentiated into three common phenotypes (Hp i-i, Hp 2-I, and Hp2-2) by means of starch gel electrophoresis at pH 8-6 (Smithies, 1955). These differences were thought to be determined by a pair of allelic genes Hp" and Hp2 (Smithies and Walker, I955, I956). However, chemical reduction of purified haptoglobin followed by electrop...

BACKGROUND AND OBJECTIVES The diagnostic and treatment of sepsis continue to challenger all, and, more specific forms to approach are absolutely necessary. The objective of this study was to use proteomics techniques, two-dimensional electrophoresis and mass spectrometry, to verify the differential protein expression between serum of patients with sepsis and health controls. METHODS Samples o...

Two ELISA procedures to determine haptoglobin (Hp) in bovine serum were developed. Equine haemoglobin was used as the solid phase. Self-developed goat polyclonal antibody (variant I) and monoclonal antibody (variant II) raised against human Hp were used. The results were compared with the guaiacol method. High correlation was found (r = 0.96 and r = 0.90, respectively) based on the results of 5...