Background It is reported that treatment of palmoplantar pustulosis (PPP) with guselkumab has greater improvement in clinical responses terms area severity index (PPPASI) score. Here, we present the effect (100 and 200 mg) on PPP-related serum proteins their association responses. Objectives To analyze effects circulating up to Week 72 evaluate Methods Serum cytokines (interleukin [IL]-17A, IL-...

Psoriasis is a chronic inflammatory skin disease. It is assumed that the plaque phenotype of psoriasis is associated with T helper (Th) 1 immune response activation, while the guttate phenotype is associated with the Th17 immune response. Previous investigations of differences in the serum levels of cytokines relative to the clinical psoriatic phenotype have yielded conflicting results. This st...

RocEas R. J. 1974. Serum opsonins and the passive transfer of protection in Bubesiu rodhaini infections of rats. InternationalJournalfor Parasitology 4: 197-201. An investigation into the protective activity of serum from rats immune to B. rodhaini and the role played by opsonins in that activity was undertaken. One, three and six infections with B. rod/mini resulted in corresponding increases ...

Serum concentrations of soluble interleukin-2 receptor (sIL-2R) were measured as a marker of immune activation in a group of 30 patients with Crohn's disease. sIL-2R concentrations were determined by enzyme linked immunosorbent assay during periods of active and inactive disease and correlated with standard parameters of disease activity. Serum concentrations of sIL-2R were significantly raised...

background: occurrence of resistance against antibioticsand inadequate efficacy of some vaccines necessitates studies ofnatural immunostimulators in aquaculture. shrimps shell derivedfrom chitosan can be used as immune stimulators in fish.objectives: in this study, the effects of oral administration ofchitosan, derived from shrimp shell, on some immune responsesand disease resistance in cyprinu...

Abstract OBJECTIVES The prognostic nutritional index (PNI) is an indicator of systemic immune-nutritional condition and a well-known biomarker in lung cancer patients. Tumour-infiltrating lymphocytes (TILs) specific histological feature cancers, influencing individual’s immunological tumour responses. However, whether PNI can reflect patients’ prognosis through local immunity such as TIL unclea...

Background. The effect of geomagnetism on human immunity has so far been studied through long-term observations. Recently, we have detected the immediate immunotropic effects disturbances geomagnetic field (Ap-index) at multiple sclerosis patients. aim this study was to identify another contingent people. Material and methods. object observation were 21 men (24-63 y) 20 women (33-62 with neuroe...

pemphigus vulgaris (pv) is an autoimmune blistering disorder of the skin or mucosa. since low vitamin d status has been linked to many immune disorders, we designed this study to compare the vitamin d status in pv patients with healthy controls.in this case-control study, vitamin d status of 32 newly diagnosed pv patients was compared with 36 healthy control subjects. all patients were selected...

background: more than 350 million people are chronic carriers of hepatitis b virus (hbv) and because of the high hbv-related morbidity and mortality, the global disease burden of hbv is substantial. in patients with hbeag–negative chronic hepatitis b (chb) with serum alanine aminotransferase (alt) levels, 1-2 × upper limit of normal (uln) and hbv dna load of 10000 to 100000 copies/ml, liver bio...