Fungi have long been associated with earthy odours. One of the main contributors to this odour is geosmin, a sesquiterpenoid metabolite produced by soil living fungi. Some food commodities are liable to contamination by geosmin producing fungi. Under favourable environmental conditions the production of geosmin occurs. One of the producers of geosmin in fruits is Penicillium expansum which also...

An efficient total synthesis of the sesquiterpenoid (−)-dehydrocostus lactone is reported. Our earlier approach by a domino enediyne metathesis was extended dienyne strategy to give access suitably functionalized hydroazulene cores. Highly stereoselective asymmetric anti aldol reactions provided enantiopure substrates for this key step our synthesis. Multiple hydroboration/oxidation resulting h...

A new rosane diterpenoid, 3a-hydroxy-5,15-rosadien-11-one (3), was isolated, together with a known rosane diterpenoid, 5,15-rosadiene-3,11-dione (4), and an aromadendrane sesquiterpenoid, ent-cyclocolorenone (5), from the Et(2)O extract of an unidentified Argentine liverwort Anastrophyllum species. Moreover, four known sesquiterpene lactones 6-9 and two known bibenzyls 10, 11 were isolated from...

Three new eudesmane type sesquiterpenoid lindenanolides E (1), F (2) and G (3), and two new aporphine alkaloid lindechunines A (18) and B (20) were isolated from roots of Lindera chunii MERR., together with seven known sesquiterpenes including a new naturally-occurring lindenanolide H (4) and eight known aporphine alkaloids. The structures of these compounds were determined by spectroscopic mea...