BACKGROUND In schizophrenic psychoses, the normal sexual dimorphism of the brain has been shown to be disrupted or even reversed. Little is known, however, at what time point in emerging psychosis this occurs. We have therefore examined, if these alterations are already present in the at-risk mental state (ARMS) for psychosis and in first episode psychosis (FEP) patients. METHODS Data from 65...

The causes and consequences of sexual dimorphism are major themes in biology. Here we explore the endocrine regulation of sexual dimorphism in horned beetles. Specifically, we explore the role of juvenile hormone (JH) in regulating horn expression in females of two species with regular sexual dimorphism for pronotal horns (females have much shorter horns than males) and a third species with a r...

Sexual dimorphism can result from sexual or ecological selective pressures, but the importance of alternative reproductive roles and trait compensation in generating phenotypic differences between the sexes is poorly understood. We evaluated morphological and behavioral sexual dimorphism in striped bark scorpions (Centruroides vittatus). We propose that reproductive roles have driven sexually d...

Gene expression differences between the sexes account for the majority of sexually dimorphic phenotypes, and the study of sex-biased gene expression is important for understanding the genetic basis of complex sexual dimorphisms. However, it has been difficult to test the nature of this relationship due to the fact that sexual dimorphism has traditionally been conceptualized as a dichotomy betwe...

Innate immunity and immunological biomarkers are believed to be interrelated with sex hormones and other neuroendocrine factors. Sexual dimorphism mechanisms may be operating in certain rheumatic and inflammatory diseases which occur more frequently in women than men, as rheumatoid arthritis (RA). Less data have been available on altered interrelations of the combined neuroendocrine and immune ...

The importance of sexual dimorphism the mouse brain metabolome was recently highlighted, in addition to a high regional specificity found between frontal cortex, cerebellum, and stem. To address origin this dimorphism, we performed gonadectomy on both sexes, followed by metabolomic study targeting 188 metabolites three regions. While sham controls, which underwent same surgical procedure withou...

background and aims. the aim of this study was to determine whether variations in the mesiodistal dimensions of mandibular canines had any role in sex determination. materials and methods. the study comprised of patients in the 19‒24-year age group (20 males and 20 females). mesiodistal dimensions of mandibular canines was measured at the maximum mesiodistal width, first intraorally, then on pl...

Introduction: Human identification plays a vital role in any crime investigation. Along with the various other established methods, cheiloscopy also plays a key role in linking the criminal with the crime. The ability of a technique in differentiating the sex of a person in the field can help in screening a large number of suspects. This study evaluated the efficacy of cheiloscopy in determinat...

Identifying sex of hatchling turtles is difficult because juveniles are not obviously externally dimorphic, and current techniques to identify sex are often logistically unfeasible for field studies. We demonstrate a widely applicable and inexpensive alternative to detect subtle but significant sexual dimorphism in hatchlings, using landmark-based geometric morphometric methods. With this appro...

Oxidative stress was recently demonstrated to affect several fitness-related traits and is now well recognized to shape animal life-history evolution. However, very little is known about how much resistance to oxidative stress is determined by genetic and environmental effects and hence about its potential for evolution, especially in wild populations. In addition, our knowledge of phenotypic s...