We study the interplay between dependent types and general computational effects. We define a language with both value types and terms, and computation types and terms, where types depend only on value terms. We use computational Σ-types to account for typedependency in the sequential composition of computations. Our language design is justified by a natural class of categorical models. We acco...

introduction: generally, nmda receptor antagonists inhibit learning and long-term potentiation (ltp). however, it has been suggested that direct tonic activation of nmda receptors, in contrast to learning, may lead to an increase in synaptic “noise”. uncompetitive nmda receptor antagonist memantine can paradoxically reverse deficits in learning and synaptic plasticity, and restore ltp impaired ...

I hope my NMDA receptors were working well in the 1980s as I try to recall the events leading up to the establishment of the mechanism of induction of LTP. My story begins in 1980 as I start my first postdoctoral position in the laboratory of Hugh McLennan, in Vancouver. Hugh was interested in l-glutamate as a neurotransmitter in the brain and was one of the pioneers in the identification of mu...

A phase of massive gravity free from pathologies can be obtained by coupling the metric to an additional spin-two field. We study the gravitational field produced by a static spherically symmetric body, by finding the exact solution that generalizes the Schwarzschild metric to the case of massive gravity. Besides the usual 1/r term, the main effects of the new spin-two field are a shift of the ...