background: aneurysm is a blood-filled bulge in the wall of vessels that occurred in abdominal aortic and cerebral vessels. the dilation of artery leads to aneurysm. methods: three dimensional modelling was utilized for a patient with cerebral aneurysm and a normal subject, and additional fluid-structural interaction simulation was performed. we consider pulsatile blood velocity as inlet, and b...

Dabigatran and rivaroxaban are novel oral anticoagulants that specifically inhibit thrombin and factor Xa, respectively. The aim of this study is to elucidate antithrombotic properties of these anticoagulant agents under arterial and venous shear conditions. Whole blood samples treated with dabigatran or rivaroxaban at 250, 500, and 1000 nM, with/without aspirin and AR-C66096, a P2Y12 antagonis...

The mechanics of cracking in fiber-reinforced ceramic matrix composites (CMCs) under general loadings remains incomplete. The present paper addresses one outstanding aspect of this problem: the development of matrix cracks in unidirectional plies under shear loading. To this end, we develop a model based on potential energy differences upstream and downstream of a fully bridged steady-state mat...

The sandstone yield strength and tensile were increased under cyclic loading paths by using the Brazilian splitting method. experiment shows that (1) specimens exhibit multiple penetrating crack damage loading, while slightly increases; (2) horizontal strain (Exx) concentration area decreases, shear (Exy) increases form changes from completely brittle to ductile mixed tensile-shear damage; (3) ...

This paper presents the simulation of the tensile modulus and the tensile strength of shor t glass fibre reinforced Polypropylene. Various formulae of the shear-lag theory were implemented in an analytical calculation program to evaluate the tensile strength values. Based on the homogenization approach the modulus values and the strength values, applying an existing failure criterion, were calc...

We present an experimental investigation of fracture in self-assembled gold nanoparticle mono- and multilayers attached to elastomer substrates and subjected to tensile stress. Imaging the fracture patterns down to the scale of single particles provides detailed information about the crack width distribution and allows us to compare the scaling of the average crack spacing as a function of stra...