BACKGROUND Antibiotic resistance of enteric pathogens particularly Shigella species, is a critical world-wide problem and monitoring their resistant pattern is essential, because the choice of antibiotics is absolutely dependent on regional antibiotic susceptibility patterns. During summer 2013, an unusual increase in number of diarrheal diseases was noticed in Isfahan, a central province of Ir...

Bdellovibrio bacteriovorus was capable of parasitizing Shigella boydii, S. flexneri, and S. sonnei. The bdellovibrio was able to produce plaques on lawns consisting of heat-killed or ultraviolet-irradiated S. boydii.

The ampicillin resistance of clinical isolates of Shigella sonnei is due to beta-lactamase production. Two kinds of resistance are found: low level, nontransmissible; and high level, tranmissible. The nontransmissible type of resistance results from a chromosomal mutation which increases the production of a beta-lactamase that hydrolyses cephalosporins relatively rapidly and gives cephalothin r...

Shigella species are generally considered to be unable to ferment salicin (Breed, Murray, and Smith, Bergey's Manual of Determinative Bacteriology, The Williams & Wilkins Co., Baltimore, 1957; Kauffmann, Enterobacteriaceae, E. Munksgaard, Copenhagen, 1950; Edwards and Ewing, Identification of Enterobacteriaceae, Burgess Publishing Co., Minneapolis, 1955). Recently, however, Ser6ny (Acta Microbi...

| Shigellosis caused by multidrug-resistant (MDR) Shigella strains is an important cause of morbidity and mortality in developing countries. Shigella strains usually harbour heterogeneous population of plasmids which can confer resistance to different antibiotics. A hospital based survey was conducted to determine the pattern of antimicrobial resistance and plasmid profiles in Shigella species ...

OBJECTIVES To determine the occurrence of class 1 and 2 integrons and antimicrobial resistance genes among sulphonamide-resistant Shigella strains isolated in Brazil during 1999-2003. METHODS Sixty-two Shigella (Shigella flexneri, n = 47 and Shigella sonnei, n = 15) were tested against 21 antimicrobial agents. The presence of integrons classes 1 and 2 and antimicrobial resistance genes was in...

The properties of three T-related phages-35, 55, and 3201-isolated from Shigella sonnei were studied. They were similar with respect to morphology of plaques, duration of the latent periods, lysis inhibition effect, and serological characteristics. These phages closely resembled the T-even phages. Phages 3201, 35, and 55 had the same host range and receptor specificity as phage T2.

Development of potent new anti-Shigella agents for rapid and specific detection and treatment is of great importance. Aptamers, nucleic acid oligomers capable of specific binding to a wide range of non-nucleic acid targets, may be of value for this purpose. In the present study, we used a Systematic Evolution of Ligands by Exponential enrichment (SELEX) process to select DNA aptamers that b...