نتایج جستجو برای: sickle cell heart function tests

تعداد نتایج: 3238778  

Journal: :The Annals of pharmacotherapy 1997
L W Howard L D Kennedy

Sickle-cell anemia is a congenital hemolytic anemia characterized by sickle-shaped RBCs. The deformed RBCs become distorted and rigid and may occlude small arterioles and capillaries leading to tissue ischemia and infarction. Sickled RBCs are too fragile to withstand the trauma of circulation, and hemolysis occurs after they enter the circulation. RBCs with a high level of Hb F are resistant to...

Journal: :Interactive cardiovascular and thoracic surgery 2010
Saif Usman Faisal B Saiful Joseph DiNatale Joseph T McGinn

Patients with sickle cell abnormalities undergoing surgery are generally considered to be at greater risk for perioperative complications. We present a 25-year-old woman with sickle cell disease (SCD) and severe aortic insufficiency. A minimally invasive, warm, beating heart approach was adopted to try and minimize the risk of sickling due to cardiopulmonary bypass (CPB), low-flow states, cold ...

2016
Abdel Badih El Ariss Mohamad Younes Jad Matar Zeina Berjaoui

OBJECTIVE The objective of this study was to assess the prevalence, gender differences, and time trends of Sickle Cell Trait in the Southern Suburb of Beirut, Lebanon, as well as to highlight the importance of screening for Sickle Cell Trait carriers in this population. Another objective was to describe a new screening technique for Sickle Cell Trait carriers. METHODS This was a retrospective...

Journal: :BMJ 1991
D Cummins R Heuschkel S C Davies

OBJECTIVE To assess compliance with oral penicillin prophylaxis in children with sickle cell disease and identify possible reasons for poor compliance. DESIGN Closed questionnaires given to parents of children with sickle cell disease and general practitioners in Brent. Urine samples from 23 children were tested for penicillin. SETTING Paediatric haematology clinic, Central Middlesex Hospit...

Journal: :Journal of clinical images and medical case reports 2023

Sickle cell disease is an autosomal recessive hematological disorder resulting from a missense point mutation in the beta chain of haemoglobin molecule. This article reports case homozygous sickle adult patient with long-standing history non-healing ulcer

2011
NI Oguanobi BJC Onwubere SO Ike BC Anisiuba EC Ejim OG Ibegbulam

BACKGROUND The prognostic implications of P-wave dispersion in patients with a variety of cardiac disease conditions are increasingly being recognised. The relationship between P-wave dispersion and left ventricular function in sickle cell anaemia is unknown. OBJECTIVE This study was aimed at evaluating the relationship between P-wave dispersion and left ventricular function in adult Nigerian...

Journal: :Blood 2001
A A Solovey A N Solovey J Harkness R P Hebbel

The vessel wall endothelium undoubtedly plays a role in the vascular pathobiology of sickle cell disease. This pilot study tested the feasibility of using an inhibitor of nuclear factor (NF)-kappa B, a transcription factor, to modify the endothelial activation state of patients with this vascular disease. For a total of 7 separate drug exposure tests, 3 subjects with sickle cell disease took su...

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