THERE IS NOW convincing evidence that myocardial ischemia may occur in the absence of symptoms.' This phenomenon, which has acquired the label "silent ischemia," is receiving considerable attention as a factor with potential prognostic significance in the management of coronary artery disease. Basic to an understanding of silent ischemia, its prevalence, precipitating factors, significance as a...

AIM To determine the clinical utility of the gated myocardial perfusion SPECT to detect silent ischemia in asymptomatic diabetic patients without previous coronary events and to evaluate the prognosis of this population. MATERIAL AND METHODS A retrospective study of 56 asymptomatic diabetics referred for a gated myocardial perfusion SPECT for diagnosis of ischemic disease was performed. The c...

INTRODUCTION Ischemic hypoxic brain injury often causes irreversible brain damage. The cascade of events leading to neuronal injury and death in ischemia includes the release of cytokines and free radicals, and induction of inflammation, apoptosis, and excitotoxicity. Reperfusion of ischemic areas could exacerbate ischemic brain damage through the generation of reactive oxygen species. The lack...

BACKGROUND Continuous ischemia monitoring helps identify patients with acute, but often silent, myocardial ischemia. Evidence suggests nurses do not activate ischemia monitoring because they think it is difficult to use. ST-Map software incorporates graphic displays to make monitoring of ongoing ischemia easier. OBJECTIVES To determine if nurses' use of and attitude toward ischemia monitoring...

CAD ! 60 years of age. Siblings with known clinical vascular disease and diabetes were excluded. The siblings underwent brain magnetic resonance imaging to identify WMH using the published criteria of the ARIC study [5] , and a maximal exercise test with thallium-201 single-photon emission tomography of the heart with rest and reperfusion imaging. Exercise-induced ischemia was defined as a reve...

Although it is now widely accepted that silent myocardial ischemia detected by ambulatory ECG monitoring (AEM) is the most common form of ischemia, the debate regarding the pathophysiological mechanisms responsible for ischemic episodes during daily life is far from being settled.1,2 Because most of the early investigations in this field had reported that the vast majority of transient ischemic...