............................................................................................................... XVII CHAPTER 1: INTRODUCTION ................................................................................... 1 1.1 NANOTECHNOLOGY ................................................................................................ 1 1.2 SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES ........

INTRODUCTION With the increase in joint revision surgery after arthroplasty, defects of hydroxyapatite (HA)-coated prostheses have been observed increasingly often. These defects adversely affect the prosthetic stability in vivo. This study has analyzed the potential effect of the adhesive strength of HA coating on the stability of HA-coated prostheses in vivo after its implantation. MATERIAL...

We report the clinical and radiographic outcome of a consecutive series of 138 hydroxyapatite-coated total knee replacements with a mean follow-up of 11 years (10 to 13). The patients were entered into a prospective study and all living patients (76 knees) were evaluated. The Hospital for Special Surgery knee score was obtained for comparison with the pre-operative situation. No patient was los...

The trabecular bone response to noncoated and fluorapatite (FA), hydroxyapatite (HA), and hydroxyapatite heat-treated (HAHT) plasma-sprayed coated implants was investigated in a goat animal model. Forty-eight cylindrical implants were inserted into the trabecular bone of the lateral and medial femoral condyles of twelve goats according to a split plot design. After an implantation period of twe...

Between June 1991 and January 1995, 42 hydroxyapatite-coated CAD-CAM femoral components were inserted in 25 patients with inflammatory polyarthropathy, 21 of whom had juvenile idiopathic arthritis. Their mean age was 21 years (11 to 35). All the patients were reviewed clinically and radiologically at one, three and five years. At the final review at a mean of 11.2 years (8 to 13) 37 hips in 23 ...

Silane-coated silica particle solutions (ISolate(TM) and PureSperm)TM)) and iodixanol (OptiPrep(TM)) were compared to polyvinylpyrrolidone (PVP)-coated silica particles (Percoll(TM)) in their efficacy to recover spermatozoa by gradient centrifugation for use in assisted reproductive procedures. Efficacy was assessed in terms of percentages of sperm recovery, sperm vitality and motility, normal ...

Magnetic nanoparticles are frequently coated with SiO2 to improve their functionality and bio-compatibility in a range of biomedical and polymer nanocomposite applications. In this paper, a scalable flame aerosol technology is used to produce highly dispersible, superparamagnetic iron oxide nanoparticles hermetically coated with silica to retain full magnetization performance. Iron oxide partic...