UNLABELLED Cardiac SPECT images are degraded by photons scattered in the thorax. Accurate correction for scatter is complicated by the nonuniform density and varied sizes of thoraxes and by the additional attenuation and scatter caused by female patients' breasts. Monte Carlo simulation is a general and accurate method for detailed modeling of scatter. Hence, for 99mTc we compared statistical r...

This research work is aimed at optimizing the availability of a framework comprising of two units linked together in series configuration utilizing Markov Model and Monte Carlo (MC) Simulation techniques. In this article, effort has been made to develop a maintenance model that incorporates three distinct states for each unit, while taking into account their different levels of deterioration. C...

MOTIVATION In molecular biology, as in many other scientific fields, the scale of analyses is ever increasing. Often, complex Monte Carlo simulation is required, sometimes within a large-scale multiple testing setting. The resulting computational costs may be prohibitively high. RESULTS We here present MCFDR, a simple, novel algorithm for false discovery rate (FDR) modulated sequential Monte ...

Hardware Acceleration of a Monte Carlo Simulation for Photodynamic Therapy Treatment Planning William Chun Yip Lo Master of Science Graduate Department of Medical Biophysics University of Toronto 2009 Monte Carlo (MC) simulations are widely used in the field of medical biophysics, particularly for modelling light propagation in biological tissue. The iterative nature of MC simulations and their...

Purpose The dosimetry procedure by simple superposition accounts only for the self-shielding of the source and does not take into account the attenuation of photons by the applicators. The purpose of this investigation is an estimation of the effects of the tandem and ovoid applicator on dose distribution inside the phantom by MCNP5 Monte Carlo simulations. Material and methods In this study,...

medicinal chemistry depends on many other disciplines ranging from organic chemistry andpharmacology to computational chemistry. typically medicinal chemists use the moststraightforward ways to prepare compounds. the validation of any design project comes from thebiological testing.studies of the binding site of vinblastine by a single cross—linking experiment identified it asbeing between resi...

in this paper, an interval approach is presented to achieve perfect selectivity and maximum sensitivity in distance relay zones, considering uncertainties. for this purpose, first, the uncertainties affecting the settings of the three zones of a distance relay are discussed. then, by using the monte-carlo simulation, the uncertainties are modelled and the impedances seen by the distance relay a...

background: gold nanoparticles (gnps) have been shown as a good radiosensitizer. in combination with radiotherapy, several studies with orthovoltage x-rays have shown considerable dose enhancement effects. this paper reports the dose enhancement factor (def) due to gnps in 18 megavoltage (mv) beams. materials and methods: different geometrical 50-nm gnps configurations at a concentration of 5 m...

background: exposure conditions in ct examinations are quite different from conventional xray. in ct examination higher dose is given to patient in comparison with the dose in other diagnostic examinations. in order to calculate organ effective dose in chest ct, monte carlo simulation has been used in this study. materials and methods: the impact survey data were used to determine the parameter...

introduction: radioiodine therapy is an effective method for treating thyroid cancer carcinoma, but it has some affects on normal tissues, hence dosimetry of vital organs are important to weigh the risks and benefits of this method. the aim of this study is to measure the absorbed doses of important organs by mcnp (monte carlo n particle) simulation and comparing the results of different method...