The acetylcholine-activated channel of chick myotube was studied using the patch-clamp method. Single channel current amplitudes were measured between -300 and +250 mV in solutions containing the permeant ions Cs+ and guanidine (G+). G+ has a relative permeability, PG/PCs, of 1.6, but carries no more than half the current that Cs+ does, with an equivalent electrochemical driving force. Experime...

Dictionary training for sparse representations involves dealing with large chunks of data and complex algorithms that determine time consuming implementations. SBO is an iterative dictionary learning algorithm based on constructing unions of orthonormal bases via singular value decomposition, that represents each data item through a single best fit orthobase. In this paper we present a GPGPU ap...

E.J. Yunis1,2, J. Zuñiga1,2,3, C.E. Larsen2,4, M. Fernández-Viña5, J. Granados6, Z.L. Awdeh4, and C.A. Alper2,4 1Dana-Farber Cancer Institute, Boston, MA, USA 2Harvard Medical School, Boston, MA, USA 3Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico 4The CBR Institute for Biomedical Research, Boston, MA, USA 5University of Texas, Houston, TX, USA 6Instituto Nacional de Cien...

OBJECTIVE To evaluate the effects of several single TMS pulses, delivered at two different inter-trial intervals (ITIs), on corticospinal excitability. METHODS Twelve healthy volunteers participated in two experimental sessions, during which TMS pulses were delivered at random or at fixed ITIs. The TMS single pulse-induced modulation of corticospinal output (motor evoked potential amplitude -...

BACKGROUND PR interval variations have recently been associated with an increased risk of long-term atrial fibrillation (AF), heart block and all-cause mortality. Genome-wide association studies have linked the PR interval with several common variants in the TBX5 gene. Several variants in the TBX5 gene, including rs7312625 and rs883079, have been associated with AF. The purpose of this study wa...

A novel distributed space-time block code (STBC) for the next generation mobile TV broadcasting is proposed. The new code provides efficient performance within a wide range of power imbalance showing strong adaptivity to the single frequency network (SFN) broadcasting deployments. The new code outperforms existing STBCs with equivalent decoding complexity and approaches those with much higher c...

Introduction Radiofrequency catheter ablation (RFCA) of typical atrial flutter (AFL) is an effective and widely performed method of treatment. Confirmation of conduction block in the cavotricuspid isthmus (CTI) is the best endpoint of the procedure. Electrophysiological measurements for validation of CTI block are usually performed using 2 or 3 catheters. However, in some situations this multi-...

Nonnegative Matrix Factorization (NMF) [1, 2] has been widely used in audio research, e.g. automatic music transcription [3], musical source separation [4], and speech enhancement [5]. The key strategy for applying NMF to audio-related tasks is to find a lower rank representation of the Short Time Fourier Transformed (STFT) input signal and use the basis vectors as dictionaries. For example, in...

This paper concerns the maximum coding rate at which data can be transmitted over a noncoherent, singleantenna, Rayleigh block-fading channel using an error-correcting code of a given blocklength with a block-error probability not exceeding a given value. A high-SNR normal approximation of the maximum coding rate is presented that becomes accurate as the signal-to-noise ratio (SNR) and the numb...