Skin is a valuable model organ system for better understanding the aging processes and related diseases in order to develop preventive therapeutic strategies. To study molecular mechanisms of skin associated diseases, researchers often usein vivo ex vivohuman skin, animal models, or cell culture systems. We present here novel long-term 3D that can be used process skin. Using primary dermal fibr...

The association between Ayurveda, anti-aging and cosmeceuticals is gaining importance in the beauty, health and wellness sector. Ayurvedic cosmeceuticals date back to the Indus Valley Civilization. Modern research trends mainly revolve around principles of anti-aging activity described in Ayurveda: Vayasthapana (age defying), Varnya (brighten skin-glow), Sandhaniya (cell regeneration), Vranarop...

Dermal white adipose tissue (dWAT) is increasingly appreciated as a special fat depot. The adipocytes in this depot exert a variety of unique effects on their surrounding cells and can undergo massive phenotypic changes. Significant modulation of dWAT content can be observed both in intrinsically and extrinsically aged skin. Specifically, skin that has been chronically photo-damaged displays a ...

Since the early days of human life on the Earth, our skin has been exposed to different levels of light. Recently, due to inevitable consequences of modern life, humans are not exposed to adequate levels of natural light during the day but they are overexposed to relatively high levels of artificial light at night. Skin is a major target of oxidative stress and the link between aging and oxidat...

Background: With the increase in life expectancy, middle aged and elderly people comprise a substantial percentage of the population worldwide. Since aging often manifests itself in the human skin, skin rejuvenation methods have gained a lot of popularity. Current medical modalities such as botulinum toxin injection, fillers, and laser therapy can provide symptomatic relief of skin aging signs ...

Laser Doppler imagery is a contemporary form biomedical science specializing in non-evasive micro-circulation investigation. This paper outlines the process and results of applying twelve different test samples to mouse skin to collect data variation of micro-circulation, then judge the effects of different formulas in skin health improvement. More specifically, it is said [15] that micro-circu...