Acute ultraviolet B (UVB) irradiation of the skin results in erythema, vasodilation, edema, and angiogenesis, which is associated with the expression of vascular endothelial growth factor (VEGF) by epidermal keratinocytes. It is unclear, however, whether VEGF is required for the damage or repair process that occurs in the skin on UVB exposure. We subjected transgenic mice that overexpress VEGF,...

Acute ultraviolet B (UVB) irradiation of the skin results in erythema, vasodilation, edema, and angiogenesis, which is associated with the expression of vascular endothelial growth factor (VEGF) by epidermal keratinocytes. It is unclear, however, whether VEGF is required for the damage or repair process that occurs in the skin on UVB exposure. We subjected transgenic mice that overexpress VEGF,...

BACKGROUND The root bark of Dictamnus dasycarpus Turcz. (Dictamni Radicis Cortex) has been widely used to treat skin diseases in Korea, and its anti-inflammatory efficacies were recently reported. OBJECTIVE The paper aims to investigate the inhibitory effects of decoction of Dictamni Radicis Cortex (DDRC) in mice with contact dermatitis (CD). MATERIALS AND METHODS We investigated the effect...

We report the rare occurrence of erythema nodosum and pyoderma gangrenosum at different times during the clinical course in a 30-year-old gentleman. He initially presented with biopsyproven erythema nodosum over both shins. He subsequently developed multiple violaceous and vegetative nodules over the upper and lower limbs. Three serial skin biopsies were performed thereafter. A diagnosis of veg...

Erythema at the base of the head is often seen in healthy adults, and this nuchal erythema could be a persistent salmon patch. Nuchal salmon patches tend to persist, and are often seen in adults. Our survey found that 71.1% (32/45) of our adult subjects without skin disease had a salmon patch at the nuchal location. This incidence is higher than that indicated in previous reports. In this study...

Contrary to their undoubted efficacy on rheumatologic diseases, potential for developing skin lesions with Tumor necrosis alpha blockers (Anti-TNF alpha) is an important question in our minds. Although we know, most of the studies and case reports in the literature show that adalimumab is an effective treatment agent on erythema nodosum, we should keep in mind this lesion as a rare paradoxical ...

Erythema multiforme (EM) is an extremely rare condition in infancy. To the best of our knowledge, there have been only three cases of neonatal EM described in the literature, and no such cases have been reported in Korea. A preterm neonate born at 35 weeks and six days of gestation presented with multiple annular erythematous patches with a targetoid shape over his entire body at 36 days of age...