Treatment of C57BL/6 mice with one transfusion of BALB/c spleen cells and anti-CD154 (anti–CD40-ligand) antibody permits BALB/c islet grafts to survive indefinitely and BALB/c skin grafts to survive for z 50 d without further intervention. The protocol induces long-term allograft survival, but the mechanism is unknown. We now report: ( a ) addition of thymectomy to the protocol permitted skin a...

Treatment of C57BL/6 mice with one transfusion of BALB/c spleen cells and anti-CD154 (anti-CD40-ligand) antibody permits BALB/c islet grafts to survive indefinitely and BALB/c skin grafts to survive for approximately 50 d without further intervention. The protocol induces long-term allograft survival, but the mechanism is unknown. We now report: (a) addition of thymectomy to the protocol permit...

Treatment of C57BL/6 mice with one transfusion of BALB/c spleen cells and anti-CD154 (anti–CD40-ligand) antibody permits BALB/c islet grafts to survive indefinitely and BALB/c skin grafts to survive for z 50 d without further intervention. The protocol induces long-term allograft survival, but the mechanism is unknown. We now report: ( a ) addition of thymectomy to the protocol permitted skin a...

Acquired tolerance to CBA skin homografts is lost in a large number of C3H mice neonatally injected with CBA spleen cells. The skin homografts persist for at least 2 months but then exhibit a chronic rejection pattern which may last up to 7 months. Histological analysis of the lymphoid tissues reveals the onset of an immune response in the axillary lymph nodes of many 4-month-old tolerant mice....

the purpose of this study was the utilization of different methods of tissue culture in proliferation of epithelial cells and autologous graft to cover surface areas without skin specifically, which is due to thermal burns more than 50%. in this experience we performed from rabbits and success to cover almost 24 times original donor site with autograft.

We have developed a biodegradable temporizing matrix (BTM) capable of supporting secondary split-skin graft-take in animal studies. We report its first long-term implantation and use as a dermal scaffold in humans. This preliminary study assesses its ability to integrate, its ease of delamination, its ability to sustain split-skin graft in complex wounds, the degree of wound contraction, and ul...

INTRODUCTION Bioresorbable polymers are often used in medical procedures. Since they are biocompatible, this class of materials is a viable alternative for cases in which tissue regeneration is strongly compromised. Bioresorbable synthetic polymers may be used as membranes to support and guide cell growth through the process of tissue repair. OBJECTIVE To assess the efficiency of a porous bio...

A 14 year old boy suffering from marked penoscrotal lymphedema is reported. Reduction scrotoplasty was done and the neoscrotum was made by combining the anterior suprapubic and posterior scrotal V-shaped flaps. A split-thickness skin graft from the thigh was placed over the denuded penis. No complication was encountered and the cosmetic result was satisfactory

Radial forearm free flap surgery is a versatile technique that is widely adopted for microvascular reconstruction of the oral, oropharyngeal and hypopharyngeal lining. Nowadays, the technique for harvesting is standardized, while reconstruction of the forearm donor site defect is somewhat controversial. The authors describe a modified closure technique developed to reduce skin tension that prov...

AIM The success of a skin graft in a cat is highly dependent on the granulation formed by the base of recipient bed. Granulation by the base of recipient bed will form after several days after injury. This research aimed to observe subjective and objective profile of skin graft recovery on forelimb of cats with different periods of donor skin placement. MATERIALS AND METHODS Nine male Indones...