Introduction: Basal cell carcinoma (BCC) is the most common cutaneous malignancy that humans acquire in the course of a lifetime (1). It is a malignant skin tumor arising from basal cells of the surface epidermis or external root sheath of the hair follicle. Case Report: 80 year old female farmer by occupation presented with chief complaints of blackish patch over the left lateral side of nose ...

Sweet syndrome or acute febrile neutrophilic dermatosis is a recurrent and rare skin disease caused by the release of cytokines, with diverse possible etiologic causes. It presents clinically with polymorphic skin lesions, fever, arthralgia, and peripheral leukocytosis. In general, it is associated with infections, malignancy and drugs. It usually regresses spontaneously and treatment is primar...

Acquired ichthyosis is a nonhereditary cutaneous disorder characterized by dry, rough skin with scaling that involves significant areas of the body. The disease most commonly manifests in adulthood and usually represents malignancy, especially hematologic disease. We report a 48-year-old woman who presented to the dermatology out-patient clinic because of severe scaling of the skin with a “dirt...

Skin cancer cells with donor genotype have been identified in allogeneic transplant patients; however, the donor contribution to the recipient's epithelial malignancy remains to be established. In this issue of the JCI, Verneuil et al. provide the first evidence for donor contribution to the malignant epithelium of skin squamous cell carcinoma in a kidney transplant recipient. This case report ...

Photoaging refers to the effects of long-term ultraviolet (UV) exposure and sun damage superimposed on intrinsically aged skin. The clinical signs associated with photoaging include dyspigmentation, laxity, a yellow hue, wrinkles, telangiectasia, a leathery appearance, and cutaneous malignancy. These changes often occur gradually as a person ages but can develop earlier if extensive UV exposure...

Extramammary Paget's disease (EMPD) is a rare cutaneous carcinoma of epidermal origin. The diagnosis is frequently delayed, and the disease tends to be associated with an underlying adnexal or internal malignancy. There have been several reports of EMPD associated with carcinoma of the bladder, prostate, kidney, and colon. The association of hepatocellular carcinoma (HCC) with EMPD appears to b...

Abstract: Mycetoma is a chronic suppurative infection affecting skin, subcutaneous tissue, and bones which common in tropical subtropical regions. The manifestations of mycetoma are painless mass, multiple sinuses purulent or seropurulent discharge that may contain grains. We reported case 39-year-old female with complaint skin mass her left breast for about year. clinical diagnosis was tumour ...

Introduction The use of vemurafenib in melanoma has improved the survival of patients; however, it is associated with skin toxicities. Aim To assess skin toxicities by dermoscopy in patients treated with vemurafenib. Material and methods Eight patients with BRAF V600 mutation positive metastatic melanoma were examined dermoscopically during vemurafenib treatment. All skin lesions occurring ...

Cutaneous cancer is now the most common human malignancy and in the UK malignant melanoma comprises 11% of all skin cancers. Eighty percent of malignant melanoma is thought to be related to excessive exposure to sunlight, particularly in childhood. Although the least common skin cancer, malignant melanoma is the most deadly. In 1999 it killed over 1600 individuals in the UK and by 2004, in the ...

Tripe palms, which described the thickening of pamar skin with increase of normal dermatoglyphics and a peculiar velvety texture, is a specific cutaneous paraneoplastic syndrome especially related to cancers of upper aerodigestive tract. Acanthosis nigricans, and florid cutaneous papillomatosis (sudden appearance of many warty skin lesions) are the most commonly associated paraneoplastic dermat...