Peptidylarginine deiminases (PADs) convert arginine within a peptide (peptidylarginine) into peptidylcitrulline. Citrullination by human PADs is important in normal physiology and inflammation. Porphyromonas gingivalis, a major pathogen in periodontitis, is the only prokaryote described to possess PAD. P. gingivalis infection may generate citrullinated peptides, which trigger anti-citrullinated...

Factors that may be significant in rationalizing physician overrides of psychiatric advance directives (PADs) are not only features of individual clinical scenarios, but also are artifacts of the faltering mental health system being navigated by both provider and patient. This system, frequently viewed as hostile to consumer choice and increasingly focused on reacting to recurrent crises, is no...

BACKGROUND many elderly suffer from urinary incontinence and use absorbent pads. Pad use per day (PPD) is a frequently used measure of urinary incontinence. Nursing home residents are often dependent on help from nursing staff to change pads. This study was performed in order to determine whether PPD is a reliable method to quantify urinary incontinence in nursing home residents. Furthermore, t...

This paper presents PADS, a policy architecture for building distributed storage systems. A policy architecture has two aspects. First, a common set of mechanisms that allow new systems to be implemented simply by defining new policies. Second, a structure for how policies, themselves, should be specified. In the case of distributed storage systems, PADS defines a data plane that provides a fix...

This paper presents PADS, a new policy architecture that makes it easier to develop distributed storage systems. PADS is based on two key ideas. First, a distributed storage system is implemented by specifying a control plane that embodies the design policy of the system over a data plane that provides a set of common mechanisms. Second, the control plane policy is separated into routing policy...

This paper proposed an efficient reduction method of voltage drop (IR) at the core of high density IC’s chips. The presented method is based on branching out several layer of metals from the I/O bond-pads of power supply and feed them to the core of the chip through a data and other non power supply pads. Hence, the up most two layers of metals (M6, M7) for seven layers of metals technology are...

Buckle-initiation techniques, such as sleepers, are usually installed to trigger lateral buckling at pre-designated locations release the axial compressive forces induced by thermal loading. Taking nonlinear pipe–soil interaction model into account, a mathematical is proposed investigate of subsea pipelines triggered sleeper. The numerical solution validated comparing with solutions in literatu...

68 October 2007 EngineerIT This article aims to automate such intuitive human skills for future sleeper inspections. Pattern recognition has been proposed for classification and results from sensors based on the abovementioned methods were fused to generate a single output condition. Final results achieved in this work indicate an overall classification rate of around 88% compared to the human ...

Psychiatric advance directives (PADs) are legal documents that allow individuals to express their wishes for future psychiatric care and to authorize a legally appointed proxy to make decisions on their behalf during incapacitating crises. PADs are viewed as an alternative to the coercive interventions that sometimes accompany mental health crises for people with mental illness. Insofar as coer...

Orientation tuning has been studied extensively in the visual system, but little is known about it in the somatosensory system. Here we investigate tuning in the second somatosensory (SII) region using a motorized stimulator that presented a small oriented bar to the 12 finger pads of digits 2-5 (D2-D5) of the macaque monkey. A subset (23%; n = 218) of the 928 SII region neurons [the same 928 n...