Abercrombie and his colleagues have accumulated evidence that changes in the heterotypic contact-inhibition response are largely responsible for the invasiveness of cells, at least in culture. We have identified a 37,000 Mr protein on the surface of mouse fibrosarcoma cells that is involved in their in vitro invasion. Blocking this protein with specific antibodies inhibits the invasion of chick...

The frictional property of soft contact lenses could have a great impact on their clinical performance. However, to date, only a handful of studies have been conducted to understand the friction mechanism(s) of the soft contact lens. In the current paper, the friction of senofilcon-A contact lenses has been studied with a stainless steel ball as the counterface in a saline solution. The load ap...

The objective of this work is to apply Atomic Force Microscopy in Peak Force mode to obtain topographic characteristics (mean roughness, root-mean-square roughness, skewness and kurtosis) and mechanical characteristics (adhesion, elastic modulus) of Siloxane-Hydrogel Soft Contact Lenses (CLs) of two different materials, Lotrafilcon B of Air Optix (AO) and Asmofilcon A of PremiO (P), after use (...

Conflicts of interest: The authors declare no conflict of interests. skin contact with consumer items, but nickel is also an important cause of occupational allergic contact dermatitis. Accordingly, excessive nickel exposure has been shown in many occupations (1–3). As it is important for clinicians to confirm and quantify occupational nickel exposure, practical and inexpensive tools are needed...

Keratoconus causes a reduction in the optical quality of the eye as a result of corneal distortion, corneal scarring and higher-order aberrations. The correction of these optical aberrations would significantly improve the visual performance of keratoconic eyes. However the first step would be to measure the optical flaws in keratoconus accurately, which in itself presents a challenge. This pap...

Six fungal species (Fusarium sp, Exophiala jeanselmei, Penicillium spp, Aspergillus niger, Paecilomyces spp, and Alternaria spp) were used to inoculate soft contact lenses. Four types of soft lenses were used: high-water (58%) and low-water (38%) content lenses and lenses that were unworn or worn for 1 day. The fungi displayed a range of macroscopic and microscopic features that allowed differe...

Parabens, methyl, ethyl, propyl, benzyl, and butyl, are the most common preservatives in use today. They are the alkyl esters of p-hydroxybenzoic acid and are used extensively because they are relatively nonirritating and nontoxic and offer good antimicrobial coverage. Testing for paraben allergen can be done by patch testing. Two cases of allergic contact dermatitis (ACD) to parabens are used ...